280 Result(s)
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Open AccessUltrasensitive detection of uveal melanoma using [18F]AlF-NOTA-PRGD2 PET imaging
Uveal melanoma (UM) is the most common primary intraocular tumor in adults, and early detection is critical to improve the clinical outcome of this disease. In this study, the diagnostic effectiveness of [18F]AlF...
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Open AccessValidation and refinement of cropland map in southwestern China by harnessing ten contemporary datasets
Accurate cropland map serves as the cornerstone of effective agricultural monitoring. Despite the continuous enrichment of remotely sensed cropland maps, pervasive inconsistencies have impeded their further ap...
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Open AccessCTR > 0.7 predicts the subgroup of lung adenocarcinomas ≤ 2 cm at risk of poor outcome treated by sublobar resection compared to lobar resection
A standard surgical procedure for patients with small early-stage lung adenocarcinomas remains unknown. Hence, we aim in this study to assess the clinical utility of the consolidation-to-tumor ratio (CTR) when...
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Attentional multi-feature fusion for spoofing-aware speaker verification
The Spoofing-Aware Speaker Verification (SASV) system is designed to protect automatic speaker verification (ASV) systems from potential speech spoofing attacks by integrating the ASV and countermeasure system...
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Pilot study of relationship between prenatal stress during the COVID-19 pandemic and social–emotional development of 12-month-old children: the mediation effects of home environment
There is increasing evidence that prenatal stress elevates the risk of children’s social–emotional development, but the mechanisms underlying this association are unclear. Home environment provides learning op...
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Entitlement Versus Obligation: The Role of Attributed Motives in Subordinate Reactions to Leader Leniency
Although previous research has examined the effectiveness of various levels of punitive reactions to misconduct, researchers have given leader leniency relatively inadequate attention. Prior studies consistent...
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Vestibular-evoked myogenic potential abnormalities in Parkinson’s disease with freezing of gait
Vestibular dysfunction is closely associated with the pathophysiology of Parkinson’s disease (PD) accompanied by freezing of gait (FOG); however, evidence supporting this clinical association is lacking. Vesti...
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Open AccessCarbon storage through China’s planted forest expansion
China’s extensive planted forests play a crucial role in carbon storage, vital for climate change mitigation. However, the complex spatiotemporal dynamics of China’s planted forest area and its carbon storage ...
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Conserving the primary forests in the Yarlung Tsangpo Grand Canyon for people and nature
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High quality hydro-char production through co-hydrothermal treatment of sewage sludge and wheat straw: novel properties
Co-hydrothermal carbonization (Co-HTC) of sewage sludge (SS) with wheat straw (WS) has emerged as a promising method for producing high quality biochar products through the utilization of low-cost biomass reso...
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Phantom study of a self-shielded X-ray bone age assessment instrument against scattered radiation in children
Hand-wrist radiography is the most common and accurate method for evaluating children’s bone age. To reduce the scattered radiation of radiosensitive organs in bone age assessment, we designed a small X-ray in...
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Multidimensional culture system for SH-SY5Y cells on microwell patterns regulated by the ROCK signaling pathway
This study presents the fabrication of polylactic acid microwell patterns using a lithography-based replica molding method for the development of three-dimensional (3D) neural cell-based assays. SH-SY5Y human ...
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Article
Blockade of Notch1 Signaling Alleviated Podocyte Injury in Lupus Nephritis Via Inhibition of NLRP3 Inflammasome Activation
To explore the role of Notch1 pathway in the pathogenesis of podocyte injury, and to provide novel strategy for podocyte repair in lupus nephritis (LN). Bioinformatics analysis and immunofluorescence assay wer...
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Unraveling the impact of external forcing and internal variability on dust storm frequency reduction in Northwest China
In this research, we initially examined the key atmospheric circulation pattern influencing the occurrence of dust storms in Northwest China during spring (February–May). We then investigated the drivers impac...
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Open AccessFlight test results for microgravity active vibration isolation system on-board Chinese Space Station
The Fluid Physics Research Rack (FPR) is a research platform employed on-board the Chinese Space Station for conducting microgravity fluid physics experiments. The research platform includes the Microgravity A...
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The Synergistic Effect Study of Lipopolysaccharide (LPS) and A53T-α-Synuclein: Intranasal LPS Exposure on the A53T-α-Synuclein Transgenic Mouse Model of Parkinson’s Disease
Aging and interactions between genetic and environmental factors are believed to be involved the chronic development of Parkinson’s disease (PD). Among PD patients, abnormally aggregated α-synuclein is a major...
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Open AccessKernel-mask knowledge distillation for efficient and accurate arbitrary-shaped text detection
Recently, segmentation-based approaches have been proposed to tackle arbitrary-shaped text detection. The trade-off between speed and accuracy is still a challenge that hinders its deployment in practical appl...
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Experimental Study for the Geogrid-Reinforced Embankment with Clay Cover Under Static and Cyclic Loading
This paper presents an analysis on a geogrid-reinforced embankment with clay-cover by model tests under static and cyclic loading. The deformation and failure surface inside the embankment were obtained by par...
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Photodegradation of anthelmintic drugs under natural sunlight and simulated irradiation: kinetics, mechanisms, transformation products, and toxicity
Albendazole (ALB) and bithionol (BIT) are two anthelmintic drugs (ADs) with high consumption from benzimidazole group and diphenylsulfide group, respectively. However, information on the transformation of the ...
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Open AccessAnalysis of data from the PALOMA-3 trial confirms the efficacy of palbociclib and offers alternatives for novel assessment of clinical trials
There remains a need for novel therapies for patients with metastatic breast cancer (MBC). We explore the use of a novel biomarker of survival that could potentially expedite the testing of novel therapies.