-
Article
Open AccessGenetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus
Rare genetic variants in toll-like receptor 7 (TLR7) are known to cause lupus in humans and mice. UNC93B1 is a transmembrane protein that regulates TLR7 localization into endosomes. In the present study, we id...
-
Article
Open AccessProportion of vitamin D deficiency in children/adolescents with type 1 diabetes: a systematic review and meta-analysis
The impact of vitamin D on type 1 diabetes has been a controversial topic in public health. Furthermore, significant differences in the proportion of vitamin D have been noted. The purpose of this systematic r...
-
Article
Bionic immunoactivator copresenting autophagy promoting and costimulatory molecules for synergistic cancer immunotherapy
Immunotherapy has great promise in improving malignant tumor treatment. However, the efficacy of existing strategies is often limited by the immunosuppressive environment. Here, we demonstrate an in situ bionic i...
-
Article
DCT-CompSegNet: fast layout segmentation in DCT compressed JPEG document images using deep feature learning
The problem of layout segmentation is still very challenging in document images like newspapers, magazines, and research articles, that have both text and non-text components arranged in an artistic way to att...
-
Article
Open AccessHighly Efficient Aligned Ion-Conducting Network and Interface Chemistries for Depolarized All-Solid-State Lithium Metal Batteries
This study introduces an innovative 3D-printed electrolyte with vertically aligned ion transport network, which contains well-dispersed nanoscale Ta-doped Li7La3Zr2O12 in a po...
-
Article
Tannic acid functionalized Cu-BTC composite for electrochemical sensing of glucose
In this experiment, a copper-based metal–organic framework (Cu-BTC) was successfully prepared and utilized to compose a copper-tannic acid (TA) complex by in situ tannic acid etching on indium tin oxide (ITO) ...
-
Article
Open AccessAnalysis of preoperative computed tomography radiomics and clinical factors for predicting postsurgical recurrence of papillary thyroid carcinoma
Postsurgical recurrence is of great concern for papillary thyroid carcinoma (PTC). We aim to investigate the value of computed tomography (CT)-based radiomics features and conventional clinical factors in pred...
-
Article
Histogram analysis of quantitative parameters from synthetic MRI: correlations with prognostic factors in nasopharyngeal carcinoma
To evaluate the correlation between histogram parameters derived from synthetic magnetic resonance imaging (SyMRI) and prognostically relevant factors in nasopharyngeal carcinoma (NPC).
-
Article
MCM8-mediated mitophagy protects vascular health in response to nitric oxide signaling in a mouse model of Kawasaki disease
Mitophagy is a major quality control pathway that removes unwanted or dysfunctional mitochondria and plays an essential role in vascular health. Here we show that MCM8 expression is significantly decreased in ...
-
Article
Open AccessAnti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies
To investigate the anti-inflammatory and antioxidative effects of gallic acid (GA) on human corneal epithelial cells (HCECs) and RAW264.7 macrophages as well as its therapeutic effects in an experimental dry e...
-
Article
Open AccessPretreatment synthetic magnetic resonance imaging predicts disease progression in nonmetastatic nasopharyngeal carcinoma after intensity modulation radiation therapy
To investigate the potential of synthetic MRI (SyMRI) in the prognostic assessment of patients with nonmetastatic nasopharyngeal carcinoma (NPC), and the predictive value when combined with diffusion-weighted ...
-
Article
Dynamic modeling and parameter identification of a track stabilizing device coupled system
To explore the relationship between the dynamic model parameters of a stabilizing device coupled system and the quality status of a ballast bed, this study establishes a dynamic model of a frame-stabilizing de...
-
Article
Open AccessThe utility of texture analysis based on quantitative synthetic magnetic resonance imaging in nasopharyngeal carcinoma: a preliminary study
Magnetic resonance imaging (MRI) is commonly used for the diagnosis of nasopharyngeal carcinoma (NPC) and occipital clivus (OC) invasion, but a proportion of lesions may be missed using non-enhanced MRI. The p...
-
Article
Open AccessAmide Proton Transfer-weighted MRI combined with serum prostate-specific antigen levels for differentiating malignant prostate lesions from benign prostate lesions: a retrospective cohort study
Early diagnosis of prostate cancer improves its prognosis, while it is essential to upgrade screening tools. This study aimed to explore the value of a novel functional magnetic resonance imaging (MRI) techniq...
-
Chapter and Conference Paper
A Method of Social Context Enhanced User Preferences for Conversational Recommender Systems
Conversational recommender systems (CRS) can dynamically capture user fine-grained preference by directly asking whether a user likes an attribute or not. However, like traditional recommender systems, accurat...
-
Article
Open AccessAdded value of histogram analysis of ADC in predicting radiation-induced temporal lobe injury of patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy
This study evaluated the predictive potential of histogram analysis derived from apparent diffusion coefficient (ADC) maps in radiation-induced temporal lobe injury (RTLI) of nasopharyngeal carcinoma (NPC) aft...
-
Article
STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential
Signal transducer and activator of transcription 5 (STAT5) promotes cell survival and instigates breast tumor formation, and in the normal breast it also drives alveolar differentiation and lactogenesis. Howev...
-
Article
Reading-related Brain Function Restored to Normal After Articulation Training in Patients with Cleft Lip and Palate: An fMRI Study
Cleft lip and/or palate (CLP) are the most common craniofacial malformations in humans. Speech problems often persist even after cleft repair, such that follow-up articulation training is usually required. How...
-
Article
A MRI-based radiomics model predicting radiation-induced temporal lobe injury in nasopharyngeal carcinoma
To develop and validate a radiomics-based model for predicting radiation-induced temporal lobe injury (RTLI) in nasopharyngeal carcinoma (NPC) by pretreatment MRI of the temporal lobe.
-
Article
Open AccessTakostubo syndrome combined with ventricular septal perforation: a case report
The precise clinical features and etiologic basis of Takotsubo syndrome remain unclear, although an association with emotional or stressful triggers has been recognized. Ventricular septal perforation is a ver...
