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Article
Open AccessDischarge locations after hospitalizations involving opioid use disorder among medicare beneficiaries
Hospitalizations involving opioid use disorder (OUD) have been increasing among Medicare beneficiaries of all ages. With rising OUD-related acute care use comes the need to understand where post-acute care is ...
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Article
Open AccessAdipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers
There is considerable evidence for the importance of the DNA methylome in metabolic health, for example, a robust methylation signature has been associated with body mass index (BMI). However, visceral fat (VF...
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Article
Open AccessDNA methylation in the adipose tissue and whole blood of Agent Orange-exposed Operation Ranch Hand veterans: a pilot study
Between 1962 and 1971, the US Air Force sprayed Agent Orange across Vietnam, exposing many soldiers to this dioxin-containing herbicide. Several negative health outcomes have been linked to Agent Orange exposu...
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Article
Gestational perfluoroalkyl substance exposure and body mass index trajectories over the first 12 years of life
Gestational exposure to perfluoroalkyl substances (PFAS), a ubiquitous class of persistent endocrine disrupting chemicals, is associated with increased risk of obesity and cardiometabolic disease. However, it ...
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Article
Open AccessSerum dioxin and DNA methylation in the sperm of operation ranch hand veterans exposed to Agent Orange
Exposure to the herbicide Agent Orange during the Vietnam War was widespread and is associated with numerous adverse health outcomes. A continuing concern of veterans is the possibility that exposure to the di...
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Article
Open AccessVariability and predictors of urinary concentrations of organophosphate flame retardant metabolites among pregnant women in Rhode Island
Organophospate flame retardants (PFRs) are chemicals of emerging concern due to restrictions on polybrominated diphenyl ether flame retardant formulations. We describe the occurrence, variability, and predicto...
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Article
Open AccessCpG island methylation profile in non-invasive oral rinse samples is predictive of oral and pharyngeal carcinoma
There are currently no screening tests in routine use for oral and pharyngeal cancer beyond visual inspection and palpation, which are provided on an opportunistic basis, indicating a need for development of n...
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Article
Open AccessHuman papillomavirus serology and tobacco smoking in a community control group
HPV infection is an established risk factor for oropharyngeal cancer, and it has been proposed that cigarette smoking may potentiate HPV infection in the oral epithelium. We sought to test the hypothesis that ...
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Article
Regular dental visits are associated with earlier stage at diagnosis for oral and pharyngeal cancer
Oral and pharyngeal cancer patients diagnosed at an advanced stage experience increased morbidity and mortality relative to those with localized disease. The aim of this study was to assess the impact of denta...
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Article
Allergies and risk of head and neck cancer
Individuals with allergies have a heightened Th2 (T helper 2) immunity, which may provide advantages in controlling tumor growth. Inverse associations have been reported among individuals with allergies and ri...
