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Article
Open AccessA coordinated progression of progenitor cell states initiates urinary tract development
The kidney and upper urinary tract develop through reciprocal interactions between the ureteric bud and the surrounding mesenchyme. Ureteric bud branching forms the arborized collecting duct system of the kidn...
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Article
Open AccessAuthor Correction: Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessSingle-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy
Cancer stem cells are critical for cancer initiation, development, and treatment resistance. Our understanding of these processes, and how they relate to glioblastoma heterogeneity, is limited. To overcome the...
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Article
Open AccessLatency and interval therapy affect the evolution in metastatic colorectal cancer
While comparison of primary tumor and metastases has highlighted genomic heterogeneity in colorectal cancer (CRC), previous studies have focused on a single metastatic site or limited genomic testing. Combinin...
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Article
Variation in genomic landscape of clear cell renal cell carcinoma across Europe
The incidence of renal cell carcinoma (RCC) is increasing worldwide, and its prevalence is particularly high in some parts of Central Europe. Here we undertake whole-genome and transcriptome sequencing of clea...