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Article
Open AccessPCR-based zebrafish model for personalised medicine in head and neck cancer
Currently, in vivo model for personalised cancer drug testing is challenging. A zebrafish larvae xenograft model has been applied in recent years to cancer research, particularly for drug testing purposes, sho...
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Article
Overexpression of TIMP-1 under the MMP-9 promoter interferes with wound healing in transgenic mice
We have generated transgenic mice harboring the murine matrix metalloproteinase 9 (MMP-9) promoter cloned in front of human TIMP-1 cDNA. The transgenic mice were viable and fertile and exhibited normal growth ...
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Article
Increased expression of collagen types I and III in human skin as a consequence of radiotherapy
To study the mechanisms of irradiation-induced fibrosis, the expression of types I and III collagen was analysed in radiotherapy-treated human skin. The subjects were ten randomly chosen women who had been tre...