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  1. Article

    Open Access

    PCR-based zebrafish model for personalised medicine in head and neck cancer

    Currently, in vivo model for personalised cancer drug testing is challenging. A zebrafish larvae xenograft model has been applied in recent years to cancer research, particularly for drug testing purposes, sho...

    Ahmed Al-Samadi, Katja Tuomainen, Anne Kivimäki in Journal of Translational Medicine (2019)

  2. No Access

    Article

    Overexpression of TIMP-1 under the MMP-9 promoter interferes with wound healing in transgenic mice

    We have generated transgenic mice harboring the murine matrix metalloproteinase 9 (MMP-9) promoter cloned in front of human TIMP-1 cDNA. The transgenic mice were viable and fertile and exhibited normal growth ...

    Tuire Salonurmi, Mataleena Parikka, Sirpa Kontusaari in Cell and Tissue Research (2004)

  3. No Access

    Article

    Increased expression of collagen types I and III in human skin as a consequence of radiotherapy

    To study the mechanisms of irradiation-induced fibrosis, the expression of types I and III collagen was analysed in radiotherapy-treated human skin. The subjects were ten randomly chosen women who had been tre...

    Riitta Riekki, Mataleena Parikka, Arja Jukkola in Archives of Dermatological Research (2002)