-
Article
Open AccessSerum protein profiling reveals an inflammation signature as a predictor of early breast cancer survival
Breast cancers exhibit considerable heterogeneity in their biology, immunology, and prognosis. Currently, no validated, serum protein-based tools are available to evaluate the prognosis of patients with early ...
-
Article
Open AccessNeuropilin-1 and placental growth factor as prognostic factors in metastatic breast cancer
Angiogenesis is crucial for tumor development, progression, and metastasizing. The most important regulator of angiogenesis is the vascular endothelial growth factor (VEGF) family, which is involved in multipl...
-
Article
Open AccessGenomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting
As the progression of low-grade diffuse astrocytomas into grade 4 tumors significantly impacts patient prognosis, a better understanding of this process is of paramount importance for improved patient care. In...
-
Article
Open AccessBreast density and the likelihood of malignant MRI-detected lesions in women diagnosed with breast cancer
To assess whether mammographic breast density in women diagnosed with breast cancer correlates with the total number of incidental magnetic resonance imaging (MRI)-detected lesions and the likelihood of the le...
-
Article
Open AccessPrevious radiotherapy improves treatment responses and causes a trend toward longer time to progression among patients with immune checkpoint inhibitor-related adverse events
Immune-related adverse events (irAEs) are frequently encountered by patients during immune checkpoint inhibitor (ICI) treatment and are associated with better treatment outcomes. The sequencing of radiotherapy...
-
Article
Open AccessAssociation of antidiabetic medication and statins with survival from ductal and lobular breast carcinoma in women with type 2 diabetes
We investigated the survival of female patients with pre-existing type 2 diabetes (T2D) diagnosed with invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) of breast, in relation to the use of ...
-
Article
Open AccessCD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer
CD73 is a cell surface ecto-5′-nucleotidase, which converts extracellular adenosine monophosphate to adenosine. High tumor CD73 expression is associated with poor outcome among triple-negative breast cancer (T...
-
Article
Open AccessHigh baseline Tie1 level predicts poor survival in metastatic breast cancer
Angiopoietin growth factors (Angs) regulate angiogenesis and lymphangiogenesis by binding to the endothelial Tie2 receptor. Ang2 expression is elevated in tissue hypoxia and inflammation, which also induce cle...
-
Article
Open AccessAssociation of antidiabetic medication and statins with breast cancer incidence in women with type 2 diabetes
To address the possible association between the use of metformin, other forms of antidiabetic medication (ADM) and statins with the incidence of breast cancer in women with type 2 diabetes (T2D).
-
Article
Increased risk of certain second primary malignancies in patients treated for well-differentiated thyroid cancer
The objective was to evaluate the incidence of second primary malignancies (SPMs) in thyroid cancer patients compared to age- and gender-matched controls without thyroid cancer from the general population of ...
-
Article
Increased expression of collagen types I and III in human skin as a consequence of radiotherapy
To study the mechanisms of irradiation-induced fibrosis, the expression of types I and III collagen was analysed in radiotherapy-treated human skin. The subjects were ten randomly chosen women who had been tre...
