Skip to main content

and
  1. Article

    Open Access

    Pre-clinical evaluation of the efficacy and safety of human induced pluripotent stem cell-derived cardiomyocyte patch

    Cell- or tissue-based regenerative therapy is an attractive approach to treat heart failure. A tissue patch that can safely and effectively repair damaged heart muscle would greatly improve outcomes for patien...

    Shigeru Miyagawa, Takuji Kawamura, Emiko Ito, Maki Takeda in Stem Cell Research & Therapy (2024)

  2. No Access

    Article

    Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia

    Critical limb ischemia (CLI) is a state of severe peripheral artery disease, with no effective treatment. Cell therapy has been investigated as a therapeutic tool for CLI, and pericytes are promising therapeut...

    Kenichiro Shimatani, Hiromu Sato in Journal of Cardiovascular Translational Re… (2024)

  3. Article

    Open Access

    Rapid and sensitive mycoplasma detection system using image-based deep learning

    A major concern in the clinical application of cell therapy is the manufacturing cost of cell products, which mainly depends on quality control. The mycoplasma test, an important biological test in cell therap...

    Hiroko Iseoka, Masao Sasai, Shigeru Miyagawa in Journal of Artificial Organs (2022)

  4. Article

    Open Access

    Cationized gelatin-HVJ envelope with sodium borocaptate improved the BNCT efficacy for liver tumors in vivo

    Boron neutron capture therapy (BNCT) is a cell-selective radiation therapy that uses the alpha particles and lithium nuclei produced by the boron neutron capture reaction. BNCT is a relatively safe tool for tr...

    Hitoshi Fujii, Akifumi Matsuyama, Hiroshi Komoda, Masao Sasai in Radiation Oncology (2011)