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Open AccessPre-clinical evaluation of the efficacy and safety of human induced pluripotent stem cell-derived cardiomyocyte patch
Cell- or tissue-based regenerative therapy is an attractive approach to treat heart failure. A tissue patch that can safely and effectively repair damaged heart muscle would greatly improve outcomes for patien...
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Open AccessRapid and sensitive mycoplasma detection system using image-based deep learning
A major concern in the clinical application of cell therapy is the manufacturing cost of cell products, which mainly depends on quality control. The mycoplasma test, an important biological test in cell therap...
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Open AccessRole and therapeutic effects of skeletal muscle-derived non-myogenic cells in a rat myocardial infarction model
Transplantation of skeletal myoblast sheets is a promising strategy for the treatment of heart failure, and its therapeutic effects have already been proven in both animal disease models and clinical trials. M...
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Open AccessTumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
Transplantation of cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSC-CMs) is a promising treatment for heart failure, but residual undifferentiated hiPSCs and malignant transformed ...
