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  1. Article

    Open Access

    A multicolor suite for deciphering population coding of calcium and cAMP in vivo

    cAMP is a universal second messenger regulated by various upstream pathways including Ca2+ and G-protein-coupled receptors (GPCRs). To decipher in vivo cAMP dynamics, we rationally designed cAMPinG1, a sensitive ...

    Tatsushi Yokoyama, Satoshi Manita, Hiroyuki Uwamori, Mio Tajiri… in Nature Methods (2024)

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  2. Article

    Open Access

    Cefcapene pivoxil-induced hypocarnitinemic hypoglycemia in elderly man with subclinical ACTH deficiency: a case report

    Drug-induced hypocarnitinemia has been noted as a cause of hypoglycemia in children. However, adult cases are extremely rare and pre-existing conditions (including endocrine disorders and frailty) have been su...

    Yoshihiro Takahashi, Masanori Murayama, Kaoru Noda… in BMC Endocrine Disorders (2023)

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    Article

    Safe administration of rituximab for follicular lymphoma after obinutuzumab infusion-related reaction

    Obinutuzumab is a novel glycoengineered, type-II anti-CD20 monoclonal antibody that was recently developed to treat follicular lymphoma (FL), the most prevalent subtype of indolent B-cell lymphoma. Several int...

    Takeshi Hara, Ryohei Suzuki, Akihisa Ohno… in International Journal of Hematology (2020)

  4. No Access

    Protocol

    In Vivo Population Imaging of Dendritic Integration in Neocortex

    Translating the advances seen recently in recording from neurons in vivo to dendritic recordings presents special difficulties. In vivo two-photon imaging of dendrites was achieved over a decade ago and is sti...

    Masanori Murayama, Matthew E. Larkum in Optical Imaging of Neocortical Dynamics (2014)

  5. Article

    Open Access

    Therapeutic targets for rheumatoid arthritis: lessons from animal models

    Yoichiro Iwakura, Shinobu Saijo, Susumu Nakae… in Arthritis Research & Therapy (2012)

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  6. No Access

    Article

    In vivo dendritic calcium imaging with a fiberoptic periscope system

    Dendritic recordings in freely moving animals present great challenges using the current approaches. Here we present in detail a microendoscopic technique (the 'periscope' method) for measuring intracellular c...

    Masanori Murayama, Matthew E Larkum in Nature Protocols (2009)

  7. No Access

    Article

    Dendritic encoding of sensory stimuli controlled by deep cortical interneurons

    Dendrites enhance the computational power of neurons by active processing of synaptic inputs but their activity, particularly in cortex, has been hard to measure. Matthew Larkum and colleagues now use a new fi...

    Masanori Murayama, Enrique Pérez-Garci, Thomas Nevian, Tobias Bock, Walter Senn… in Nature (2009)

  8. No Access

    Article

    Cushing’s syndrome caused by an ectopic pituitary adenoma of the sphenoid sinus: Adrenal crisis after partial resections of the adenoma

    A 60-year-old woman with an 8-year history of Cushing’s syndrome was evaluated. Biochemical data were consistent with those of Cushing’s disease. Plasma ACTH levels responded paradoxically to GnRH. MRI demonst...

    Hiroyuki Morita, Keigo Yasuda, Kazuya Nkashima, Nobuyasu Noritake… in Endocrine Pathology (1994)