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  1. No Access

    Article

    Cardiac differentiation of chimpanzee induced pluripotent stem cell lines with different subspecies backgrounds

    The comparative analysis between humans and non-human primates is an instrumental approach for elucidating the evolutional traits and disease propensity of humans. However, in primates, cross-species analyses ...

    Mika Takahi, Yusuke Hamazaki, Kiyoshi Ohnuma… in In Vitro Cellular & Developmental Biology … (2024)

  2. No Access

    Article

    Generation of chimpanzee induced pluripotent stem cell lines for cross-species comparisons

    As humans’ closest living relatives, chimpanzees offer valuable insights into human evolution. However, technical and ethical limitations hinder investigations into the molecular and cellular foundations that ...

    Masanori Imamura, Risako Nakai, Mari Ohnuki… in In Vitro Cellular & Developmental Biology … (2024)

  3. No Access

    Article

    Molecular histology of spermatogenesis in the Japanese macaque monkey (Macaca fuscata)

    Non-human primates are our closest relatives and therefore offer valuable comparative models for human evolutionary studies and biomedical research. As such, Japanese macaques (Macaca fuscata) have contributed to...

    Sawako Okada, Kota Kuroki, Cody A. Ruiz, Anthony J. Tosi, Masanori Imamura in Primates (2021)

  4. Article

    Open Access

    Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata)

    Non-human primates are our closest relatives and are of special interest for ecological, evolutionary and biomedical research. The Japanese macaque (Macaca fuscata) has contributed to the progress of primatology ...

    Risako Nakai, Mari Ohnuki, Kota Kuroki, Haruka Ito, Hirohisa Hirai… in Scientific Reports (2018)

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  5. No Access

    Article

    Sphere-formation culture of testicular germ cells in the common marmoset, a small New World monkey

    Spermatogonia are specialized cells responsible for continuous spermatogenesis and the production of offspring. Because of this biological property, in vitro culture of spermatogonia provides a powerful method...

    Zachary Yu-Ching Lin, Orie Hikabe, Sadafumi Suzuki, Takamasa Hirano… in Primates (2016)

  6. No Access

    Article

    Cell-intrinsic reprogramming capability: gain or loss of pluripotency in germ cells

    In multicellular organisms, germ cells are an extremely specialized cell type with the vital function of transmitting genetic information across generations. In this respect, they are responsible for the perpe...

    Masanori Imamura, Zachary Yu-Ching Lin, Hideyuki Okano in Reproductive Medicine and Biology (2013)

  7. No Access

    Protocol

    Derivation of Induced Pluripotent Stem Cells by Retroviral Gene Transduction in Mammalian Species

    Pluripotent stem cells can provide us with an enormous cell source for in vitro model systems for development. In 2006, new methodology was designed to generate pluripotent stem cells directly from somatic cel...

    Masanori Imamura, Hironobu Okuno, Ikuo Tomioka, Yoshimi Kawamura… in Genomic Imprinting (2012)

  8. Article

    Open Access

    Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells

    We previously identified a set of genes called ECATs (ES cell-associated transcripts) that are expressed at high levels in mouse ES cells. Here, we examine the expression and DNA methylation of ECATs in somati...

    Masanori Imamura, Kyoko Miura, Kumiko Iwabuchi… in BMC Developmental Biology (2006)

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