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Article
Open AccessEfficient hepatocyte differentiation of primary human hepatocyte-derived organoids using three dimensional nanofibers (HYDROX) and their possible application in hepatotoxicity research
Human liver organoids are in vitro three dimensionally (3D) cultured cells that have a bipotent stem cell phenotype. Translational research of human liver organoids for drug discovery has been limited by the c...
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Article
Open AccessFace-selective tungstate ions drive zinc oxide nanowire growth direction and dopant incorporation
Tailoring the elemental do** of inorganic nanowires remains an important challenge due to complex dopant incorporation pathways. Here we report that the face-selectivity of tungstate ions controls growth dir...
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Article
Open AccessSubstantial Narrowing on the Width of “Concentration Window” of Hydrothermal ZnO Nanowires via Ammonia Addition
A crystal growth of hydrothermal ZnO nanowires essentially requires a concentration control within so-called “concentration window”, where the anisotropic crystal growth of ZnO nanowires preferentially occurs....
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Article
PM2.5 Particle Detection in a Microfluidic Device by Using Ionic Current Sensing
We have demonstrated a PM2.5 analysis method that adds information on the number concentration and size by using microfluidic-based ionic current sensing with a bridge circuit. The bridge circuit allows for suppr...
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Article
Effect of DNA Methylation on the Velocity of DNA Translocation through a Nanochannel
Here, we report the effect of DNA methylation on the velocity of DNA translocation through a nanochannel, as determined by measuring differences in translocation velocities between methylated and non-methylate...
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Article
Nanostructures Integrated with a Nanochannel for Slowing Down DNA Translocation Velocity for Nanopore Sequencing
Here, we developed a device integrated with a nanochannel and nanostructures to slow DNA translocation velocity. We found that translocation velocity of a single DNA molecule inside a nanochannel was decreased...
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Article
Open AccessA millisecond micro-RNA separation technique by a hybrid structure of nanopillars and nanoslits
A millisecond micro-RNA separation of a mixture of total RNA and genomic DNA, extracted from cultured HeLa cells, was successfully achieved using a hybrid structure of nanopillars and nanoslits contained insid...
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Article
Open AccessThree-dimensional Nanowire Structures for Ultra-Fast Separation of DNA, Protein and RNA Molecules
Separation and analysis of biomolecules represent crucial processes for biological and biomedical engineering development; however, separation resolution and speed for biomolecules analysis still require impro...
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Article
Self-assembled Nanowire Arrays as Three-dimensional Nanopores for Filtration of DNA Molecules
Molecular filtration and purification play important roles for biomolecule analysis. However, it is still necessary to improve efficiency and reduce the filtration time. Here, we show self-assembled nanowire a...
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Article
Open AccessNanoscale Size-Selective Deposition of Nanowires by Micrometer Scale Hydrophilic Patterns
Controlling the post-growth assembly of nanowires is an important challenge in the development of functional bottom-up devices. Although various methods have been developed for the controlled assembly of nanow...
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Article
Open AccessCellulose Nanofiber Paper as an Ultra Flexible Nonvolatile Memory
On the development of flexible electronics, a highly flexible nonvolatile memory, which is an important circuit component for the portability, is necessary. However, the flexibility of existing nonvolatile mem...
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Article
Open AccessUltrafast and Wide Range Analysis of DNA Molecules Using Rigid Network Structure of Solid Nanowires
Analyzing sizes of DNA via electrophoresis using a gel has played an important role in the recent, rapid progress of biology and biotechnology. Although analyzing DNA over a wide range of sizes in a short time...
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Article
Open AccessScaling Effect on Unipolar and Bipolar Resistive Switching of Metal Oxides
Electrically driven resistance change in metal oxides opens up an interdisciplinary research field for next-generation non-volatile memory. Resistive switching exhibits an electrical polarity dependent “bipola...
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Article
Esophageal Replacement Using a Reversed Gastric Tube for Lye Stricture in a Child: Report of a Case
A 5-year-old girl ingested lye, a detergent used in electric dishwashers. She was transferred to our hospital after balloon dilatation, performed for stenosis resulting from corrosive esophagitis, was complica...
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Chapter and Conference Paper
Optimal Design of the Micromixer using Nonhomogeneous Multilayer Laminar Flow
An efficient micromixer using nonhomogeneous multilayer in the laminar flow regime is described. In order to increase the mixing efficiency, the CFD simulation was used to optimize the width of the multilayers...
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Chapter and Conference Paper
Evaluation of Silanol Concentration on Quartz Glass Surface for EOF Stability of CE Chip
The effects of heat treatment during fabrication process and NaOH treatment after fabrication on surface silanol (Si-OH) concentration profile are discussed. FTIR-ATR (Fourier transform Infrared Spectroscopy -...
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Article
An extremely large solitary primary paraganglioma of the lung: Report of a case
We present herein the case of a 38-year-old woman found to have an extremely large solitary primary paraganglioma of the lung. The patient presented with chest pain on exertion and a mass was discovered in the...
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Article
The Impact of Maternal Terbutaline Administration on Lung Growth Following Prenatal Tracheal Occlusion
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Article
Superconductivity and scanning tunneling microscopy (STM) / spectroscopy (STS) of transition metal oxide artificial lattices
High Tc superconducting artificial lattices and superlattices have been constructed by a laser molecular beam epitaxy. Layer-by-layer growth method controlled by RHEED and STM is a promising method for the constr...
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Article
Strained LiNbo3/Sapphire Heterostructures Grown by Pulsed Laser Deposition
Thin LiNbO3 films are deposited on (001) sapphire substrates by Ar F pulsed laser ablation. The films are evaluated by X-ray diffraction analysis at various temperatures, as well as high-resolution transmission e...
