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Article
Open AccessPrevalence of pathogenic germline variants in the circulating tumor DNA testing
Somatic and germline variants are not distinguishable by circulating tumor DNA (ctDNA) testing without analyzing non-tumor samples. Although confirmatory germline testing is clinically relevant, the criteria f...
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Article
Open AccessInter-assay variability of next-generation sequencing-based gene panels
Tumor heterogeneity has been known to cause inter-assay discordance among next-generation sequencing (NGS) results. However, whether preclinical factors such as sample type, sample quality and analytical featu...
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Article
Open AccessRepeated talaporfin sodium photodynamic therapy for esophageal cancer: safety and efficacy
Talaporfin sodium photodynamic therapy (tPDT) is an effective salvage treatment for local failure after chemoradiotherapy for esophageal cancer. Repeated tPDT could also be indicated for local recurrence or re...
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Article
Open AccessDistinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells
Epidermal growth factor receptor (EGFR) plays a pivotal role in the pathophysiology of esophageal squamous cell carcinoma (ESCC). However, the clinical effects of EGFR inhibitors on ESCC are controversial. Thi...
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Article
Meso and racemo Additions in Propagation for Radical Polymerization of Dialkyl Fumarates I. Stereoregularity of Poly(dialkyl fumarate)s
The polymerization temperature dependence of the stereochemical configuration of some poly(dialkyl fumarate)s as poly(substituted methylene) was investigated by the use of 13C NMR spectroscopy in order to clarify...
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Article
Meso and racemo Additions in Propagation for Radical Polymerization of Dialkyl Fumarates II. Determination of the Absolute Rate Constants
The propagation process in radical polymerization of dialkyl fumarates (DRF) was investigated. The propagation rate constants (kp) for some DRFs were determined by ESR spectroscopy. It was revealed that kp increa...
