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  1. No Access

    Article

    Evidence for widespread cytoplasmic structuring into mesoscale condensates

    Compartmentalization is an essential feature of eukaryotic life and is achieved both via membrane-bound organelles, such as mitochondria, and membrane-less biomolecular condensates, such as the nucleolus. Know...

    Felix C. Keber, Thao Nguyen, Andrea Mariossi, Clifford P. Brangwynne… in Nature Cell Biology (2024)

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    Chapter

    Asymmetries in Cell Division, Cell Size, and Furrowing in the Xenopus laevis Embryo

    Asymmetric cell divisions produce two daughter cells with distinct fate. During embryogenesis, this mechanism is fundamental to build tissues and organs because it generates cell diversity. In adults, it rema...

    Jean-Pierre Tassan, Martin Wühr… in Asymmetric Cell Division in Development, D… (2017)

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    Article

    Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytes

    Separase not only triggers anaphase of meiosis I by proteolytic cleavage of cohesin on chromosome arms, but in vitro vertebrate separase also acts as a direct inhibitor of cyclin-dependent kinase 1 (Cdk1) on libe...

    Ingo H. Gorr, Alexandra Reis, Dominik Boos, Martin WÜhr… in Nature Cell Biology (2006)