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Article
Advances in digital anthropometric body composition assessment: neural network algorithm prediction of appendicular lean mass
Currently available anthropometric body composition prediction equations were often developed on small participant samples, included only several measured predictor variables, or were prepared using convention...
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Article
Evidence for widespread cytoplasmic structuring into mesoscale condensates
Compartmentalization is an essential feature of eukaryotic life and is achieved both via membrane-bound organelles, such as mitochondria, and membrane-less biomolecular condensates, such as the nucleolus. Know...
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Chapter
Amputations and Rehabilitation
Amputation of a lower limb is a life-altering event and is often perceived as a failure of conservative treatment or an inevitable, unpreventable consequence of diabetes. This is erroneous, and an amputation s...
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Article
Open AccessHigh-resolution landscape of an antibiotic binding site
Antibiotic binding sites are located in important domains of essential enzymes and have been extensively studied in the context of resistance mutations; however, their study is limited by positive selection. U...
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Chapter
Sintering: A Method for Construction of Off-Earth Infrastructure from Off-Earth Materials
The establishment of a self-sustaining human presence on planetary bodies depends on the capability to build infrastructure. Infrastructure, such as roads, habitations, garages, and landing pads, will be neces...
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Article
Open AccessDifferential nuclear import sets the timing of protein access to the embryonic genome
The development of a fertilized egg to an embryo requires the proper temporal control of gene expression. During cell differentiation, timing is often controlled via cascades of transcription factors (TFs). Ho...
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Article
Open AccessAntibody targeting of E3 ubiquitin ligases for receptor degradation
Most current therapies that target plasma membrane receptors function by antagonizing ligand binding or enzymatic activities. However, typical mammalian proteins comprise multiple domains that execute discrete...
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Article
Open AccessReduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
Several mutations that cause Parkinson’s disease (PD) have been identified over the past decade. These account for 15–25% of PD cases; the rest of the cases are considered sporadic. Currently, it is accepted t...
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Article
Hierarchical planning with state abstractions for temporal task specifications
We often specify tasks for a robot using temporal language that can include different levels of abstraction. For example, the command “go to the kitchen before going to the second floor” contains spatial abstract...
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Article
Open AccessSalivary anti-nuclear antibody (ANA) mirrors serum ANA in systemic lupus erythematosus
To assay salivary anti-nuclear antibody (ANA) and its isotypes in patients with systemic lupus erythematosus (SLE) and to investigate relevant clinical associations.
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Chapter and Conference Paper
Multi-class Sentiment Classification for Customers’ Reviews
The rise of e-commerce due to the Covid-19 situation is becoming more significant in 2021. It could lead to great demands to understand customers’ opinions usually shown in their reviews. An e-commerce platfor...
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Article
Affordance-based robot object retrieval
Natural language object retrieval is a highly useful yet challenging task for robots in human-centric environments. Previous work has primarily focused on commands specifying the desired object’s type such as ...
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Article
Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated dihydrouridylation
Epitranscriptomic RNA modifications can regulate RNA activity; however, there remains a major gap in our understanding of the RNA chemistry present in biological systems. Here we develop RNA-mediated activity-...
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Article
Open AccessPlatelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP
Following their inoculation by the bite of an infected Anopheles mosquito, the malaria parasite sporozoite forms travel from the bite site in the skin into the bloodstream, which transports them to the liver. The...
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Chapter
Vietnamese Pre-service Teachers’ Perceived Development of Employability Capital in Synchronous Learning Amidst the Pandemic
For the purpose of examining our hypothesis, that synchronous learning (SL) and students’ employability are connected in Vietnamese higher education (HE), we sought to obtain Vietnamese English pre-service tea...
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Article
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
Activating the intrinsic apoptosis pathway with small molecules is now a clinically validated approach to cancer therapy. In contrast, blocking apoptosis to prevent the death of healthy cells in disease settin...
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Article
Open AccessIn vivo model of human post-traumatic heterotopic ossification demonstrates early fibroproliferative signature
The relationship between the tissue injury healing response and development of heterotopic ossification (HO) is poorly understood. Here we compare a rat blast model and human traumatized muscle from a blast in...
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Article
Enhanced cell–cell contact stability and decreased N-cadherin-mediated migration upon fibroblast growth factor receptor-N-cadherin cross talk
N-cadherin adhesion has been reported to enhance cancer and neuronal cell migration either by mediating actomyosin-based force transduction or initiating fibroblast growth factor receptor (FGFR)-dependent bioc...
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Article
Open AccessRespiration rate and volume measurements using wearable strain sensors
Current methods for continuous respiration monitoring such as respiratory inductive or optoelectronic plethysmography are limited to clinical or research settings; most wearable systems reported only measures ...
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Protocol
Immunofluorescence of Microtubule Assemblies in Amphibian Oocytes and Early Embryos
Amphibian oocytes and embryos are classical models to study cellular and developmental processes. For these studies, it is often advantageous to visualize protein organization. However, the large size and yolk...
