6 Result(s)

Article

Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study

Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study...

Anna H. Ou, Sara B. Rosenthal, Mazda Adli, Kazufumi Akiyama… in Translational Psychiatry (2024)

Article

Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

Lithium is regarded as the first-line treatment for bipolar disorder (BD), a severe and disabling mental health disorder that affects about 1% of the population worldwide. Nevertheless, lithium is not consiste...

Azmeraw T. Amare, Anbupalam Thalamuthu, Klaus Oliver Schubert… in Molecular Psychiatry (2023)

Article

Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw T. Amare… in Translational Psychiatry (2022)

Article

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

Lithium is the gold standard therapy for Bipolar Disorder (BD) but its effectiveness differs widely between individuals. The molecular mechanisms underlying treatment response heterogeneity are not well unders...

Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw T. Amare… in Translational Psychiatry (2021)

Article

Plasma Leptin and Antipsychotic-Induced Body Weight Gain

Palmiero Monteleone, Michele Fabrazzo, Mario Maj in Neuropsychopharmacology (2005)

Article

Blood Levels of the Endocannabinoid Anandamide are Increased in Anorexia Nervosa and in Binge-Eating Disorder, but not in Bulimia Nervosa

The endocannabinoid system, consisting of two cannabinoid receptors (CB₁ and CB₂) and the endogenous ligands anandamide (arachidonoylethanolamide (AEA)) and 2-arachidonoylglycerol (2-AG), has been shown to contro...

Palmiero Monteleone, Isabelle Matias, Vassilis Martiadis… in Neuropsychopharmacology (2005)