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Article
Open AccessMetabolic Syndrome features and risk of neural tube defects
Maternal obesity and pre-pregnancy diabetes mellitus, features of the metabolic syndrome (MetSyn), are individual risk factors for neural tube defects (NTD). Whether they, in combination with additional featur...
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Article
Open AccessIncreased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel
The administration of antiplatelet drugs before coronary artery bypass graft surgery (CABG) is associated with an increased risk of major hemorrhage and related surgical reexploration. Little is known about th...
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Article
Open AccessUse of antihypertensive medications in pregnancy and the risk of adverse perinatal outcomes: McMaster Outcome Study of Hypertension In Pregnancy 2 (MOS HIP 2)
Uncertainty remains about the potential harmful effects of antihypertensive therapy on the develo** fetus, especially for beta-blockers (βb).
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Article
Genetics University of Toronto Thrombophilia Study in Women (GUTTSI): genetic and other risk factors for venous thromboembolism in women
Women may be at increased risk for venous thromboembolism (VTE) as compared with men. We studied the effects of genetic and biochemical markers of thrombophilia in women, in conjunction with other established ...