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Article
Safety Profile and Costs of Related Adverse Events of Trastuzumab Emtansine for the Treatment of HER2-Positive Locally Advanced or Metastatic Breast Cancer Compared to Capecitabine Plus Lapatinib from the Perspective of the Canadian Health-Care System
Trastuzumab emtansine (T-DM1, KADCYLA®) is an antibody–drug conjugate comprised of the cytotoxic agent DM1 and trastuzumab (HERCEPTIN®). The safety profile of T-DM1 in human epidermal growth factor receptor 2 (HE...
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Article
Open AccessIncreased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel
The administration of antiplatelet drugs before coronary artery bypass graft surgery (CABG) is associated with an increased risk of major hemorrhage and related surgical reexploration. Little is known about th...