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Article
Venlafaxine’s effect on resilience to stress is associated with a shift in the balance between glucose and fatty acid utilization
Brain metabolism is a fundamental process involved in the proper development of the central nervous system and in the maintenance of the main higher functions in humans. As consequence, energy metabolism imbal...
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Article
Open AccessResilience to chronic mild stress-induced anhedonia preserves the ability of the ventral hippocampus to respond to an acute challenge
Stress is a major precipitating factor for psychiatric disorders and its effects may depend on its duration and intensity. Of note, there are differences in individual susceptibility to stress, with some subje...
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Article
Open AccessMetabolomic signature and mitochondrial dynamics outline the difference between vulnerability and resilience to chronic stress
Stress is the foremost environmental factor involved in the pathophysiology of major depressive disorder (MDD). However, individual differences among people are critical as some people exhibit vulnerability wh...
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Article
Open AccessMicrobial biofilm correlates with an increased antibiotic tolerance and poor therapeutic outcome in infective endocarditis
Infective endocarditis (IE) is associated with high rates of mortality. Prolonged treatments with high-dose intravenous antibiotics often fail to eradicate the infection, frequently leading to high-risk surgic...
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Chapter and Conference Paper
Macroeconomic Forecasting with Agent-Based Models: Prediction and Simulation of the Impact of Public Policies on SMEs
The aim of this chapter is to show and discuss an integrated scheme of the MOSIPS project. This project, using an agent-based model methodology, focuses on simulating and evaluating policies for small and medi...
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Chapter and Conference Paper
MOSIPS Agent-Based Model for Predicting and Simulating the Impact of Public Policies on SMEs
This paper presents MOSIPS (MOdel of Simulation of Impacts of Public Policies on SMEs), a multi-agent model of an open economy. It is part of a user-friendly object-oriented interactive intelligent policy simu...