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  1. Article

    Open Access

    The African coelacanth genome provides insights into tetrapod evolution

    The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of lobe-finned fish was thought to have become extinct 70 million years ago. The modern coelacanth looks remarkably similar...

    Chris T. Amemiya, Jessica Alföldi, Alison P. Lee, Shaohua Fan, Hervé Philippe in Nature (2013)

  2. Article

    Open Access

    The Lungfish Transcriptome: A Glimpse into Molecular Evolution Events at the Transition from Water to Land

    Lungfish and coelacanths are the only living sarcopterygian fish. The phylogenetic relationship of lungfish to the last common ancestor of tetrapods and their close morphological similarity to their fossil anc...

    Maria Assunta Biscotti, Marco Gerdol, Adriana Canapa, Mariko Forconi in Scientific Reports (2016)

  3. Article

    Open Access

    Evolution of Th2 responses: characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity

    Th2 immunity is a primary host defence against metazoan pathogens and two of the important cytokines involved in this immune response in mammals are IL-4 and IL-13. Recently the origin and evolution of Th2 imm...

    Valentina Stocchi, Tiehui Wang, Elisa Randelli, Massimo Mazzini in Scientific Reports (2017)

  4. Article

    Open Access

    Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry

    The quality and relative amounts of dietary lipids may affect the health and growth of cultured Atlantic salmon. So far, little is known about their effects on the performance of the fish immune system during ...

    Mahsa Jalili, Yang **, Atle M. Bones, Yngvar Olsen, Olav Vadstein in Scientific Reports (2019)

  5. Article

    Open Access

    Molecular and Structural Characterization of MHC Class II β Genes Reveals High Diversity in the Cold-Adapted Icefish Chionodraco hamatus

    This study reports the presence of two distinct MHC class II β genes in the Antarctic icefish Chionodraco hamatus, belonging to the classical (ChhaDAB) and nonclassical (ChhaDBB) evolutionary lineages. By the app...

    Marco Gerdol, Daniela Lucente, Francesco Buonocore, Elia Poerio in Scientific Reports (2019)

  6. Article

    Open Access

    The transcriptome of the newt Cynops orientalis provides new insights into evolution and function of sexual gene networks in sarcopterygians

    Amphibians evolved in the Devonian period about 400 Mya and represent a transition step in tetrapod evolution. Among amphibians, high-throughput sequencing data are very limited for Caudata, due to their large...

    Maria Assunta Biscotti, Federica Carducci, Marco Barucca in Scientific Reports (2020)

  7. Article

    Open Access

    Investigation of the activity of transposable elements and genes involved in their silencing in the newt Cynops orientalis, a species with a giant genome

    Caudata is an order of amphibians with great variation in genome size, which can reach enormous dimensions in salamanders. In this work, we analysed the activity of transposable elements (TEs) in the transcrip...

    Federica Carducci, Elisa Carotti, Marco Gerdol, Samuele Greco in Scientific Reports (2021)