24 Result(s)
within
Marc Lipman
English
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Article
Open AccessAuthor Correction: Hidden loss to follow-up among tuberculosis patients managed by public–private mix institutions in South Korea
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Article
Open AccessThe roles of neutrophils in non-tuberculous mycobacterial pulmonary disease
Non-tuberculous Mycobacterial Pulmonary Disease (NTM-PD) is an increasingly recognised global health issue. Studies have suggested that neutrophils may play an important role in controlling NTM infection and c...
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Article
Open AccessHidden loss to follow-up among tuberculosis patients managed by public–private mix institutions in South Korea
In South Korea, public–private mix (PPM) was launched in 2011. This retrospective cohort study sought to determine the rate of loss to follow-up (LTFU) among drug-susceptible tuberculosis (DS-TB) patients in a...
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Article
Open AccessDevelopment of a fixed module repertoire for the analysis and interpretation of blood transcriptome data
As the capacity for generating large-scale molecular profiling data continues to grow, the ability to extract meaningful biological knowledge from it remains a limitation. Here, we describe the development of ...
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Tuberculosis in People Living with HIV
Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection occurs throughout the world, and remains a significant challenge to TB control. Both HIV and TB cause immune dysregulation that can result .....
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Post-Tuberculosis Infections and Chronic Lung Disease
There is an increased awareness of the long-term physical, psychological and socioeconomic consequences that can follow apparently successful treatment for tuberculosis (TB). In this chapter, we describe the h.....
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HIV and TB
HIV and tuberculosis (TB) co-infection remains a major global healthcare challenge. HIV is the strongest single risk factor for the development of TB disease—which itself is the leading cause of death in peopl...
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Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings
The risk of tuberculosis (TB) is variable among individuals with latent Mycobacterium tuberculosis infection (LTBI), but validated estimates of personalized risk are lacking. In pooled data from 18 systematically...
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Open AccessAnticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes
The COVID-19 pandemic has currently overtaken every other health issue throughout the world. There are numerous ways in which this will impact existing public health issues. Here we reflect on the interactions...
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Article
Develo** a pathway for the diagnosis and management of ocular tuberculosis. The pan-LOndon Ocular tuberculosis Pathway—LOOP
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Chapter
Global Epidemiology of NTM Disease (Except Northern America)
This chapter summarizes the epidemiology of NTM isolations and NTM disease worldwide. Understanding of the global epidemiology of NTM disease is evolving due to heterogeneity of NTM isolation from continent to...
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Article
Open AccessTrends in, and factors associated with, HIV infection amongst tuberculosis patients in the era of anti-retroviral therapy: a retrospective study in England, Wales and Northern Ireland
HIV increases the progression of latent tuberculosis (TB) infection to active disease and contributed to increased TB in the UK until 2004. We describe temporal trends in HIV infection amongst patients with TB...
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Open AccessHigh mortality in patients with Mycobacterium avium complex lung disease: a systematic review
The incidence of nontuberculous mycobacterial (NTM) pulmonary disease caused by Mycobacterium avium complex (MAC) in apparently immune-competent people is increasing worldwide. We performed a systematic review of...
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Article
Open AccessResilience and Physical and Mental Well-Being in Adults with and Without HIV
Resilience has been related to improved physical and mental health, and is thought to improve with age. No studies have explored the relationship between resilience, ageing with HIV, and well-being. A cross se...
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Article
Open AccessSpot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis
The use of early morning sputum samples (EMS) to diagnose tuberculosis (TB) can result in treatment delay given the need for the patient to return to the clinic with the EMS, increasing the chance of patients ...
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Open AccessAn association between pulmonary Mycobacterium avium-intracellulare complex infections and biomarkers of Th2-type inflammation
The rising incidence of pulmonary Mycobacterium avium-intracellulare complex (MAI) infection is unexplained but parallels the growing world-wide epidemic of allergic disease. We hypothesized an association betwee...
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Open AccessGenetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance
The largest outbreak of isoniazid-resistant (INH-R) Mycobacterium tuberculosis in Western Europe is centred in North London, with over 400 cases diagnosed since 1995.
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Article
Open AccessVariation in C - reactive protein response according to host and mycobacterial characteristics in active tuberculosis
The C - reactive protein (CRP) response is often measured in patients with active tuberculosis (TB) yet little is known about its relationship to clinical features in TB, or whether responses differ between et...
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Open AccessPulmonary Mycobacterium avium-intracellulare is the main driver of the rise in non-tuberculous mycobacteria incidence in England, Wales and Northern Ireland, 2007–2012
The incidence of non-tuberculous mycobacteria (NTM) isolation from humans is increasing worldwide. In England, Wales and Northern Ireland (EW&NI) the reported rate of NTM more than doubled between 1996 and 200...
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Open AccessUniting to end the TB epidemic: advances in disease control from prevention to better diagnosis and treatment
Tuberculosis is a major global cause of morbidity and mortality. Despite recent advances in containing the epidemic, several challenges continue to slow progress towards elimination including the continuing im...
