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  1. Article

    Open Access

    Conditional versus non-conditional incentives to maximise return of participant completed questionnaires in clinical trials: a cluster randomised study within a trial

    High participant retention enhances the validity of clinical trials. A monetary incentive can increase retention, but it is not known if when it is provided and if it is conditional matters. We aimed to determ...

    Johanna Cook, Jonathan A. Cook, Emily Bongard, Carl Heneghan, Chris C. Butler in Trials (2023)

  2. Article

    Open Access

    Cost-effectiveness of adding oseltamivir to primary care for influenza-like-illness: economic evaluation alongside the randomised controlled ALIC4E trial in 15 European countries

    Oseltamivir is usually not often prescribed (or reimbursed) for non-high-risk patients consulting for influenza-like-illness (ILI) in primary care in Europe. We aimed to evaluate the cost-effectiveness of addi...

    **ao Li, Joke Bilcke, Alike W. van der Velden in The European Journal of Health Economics (2023)

  3. Article

    Open Access

    Direct and Indirect Costs of Influenza-Like Illness Treated with and Without Oseltamivir in 15 European Countries: A Descriptive Analysis Alongside the Randomised Controlled ALIC4E Trial

    Influenza-like illness (ILI) leads to a substantial disease burden every winter in Europe; however, oseltamivir is not frequently prescribed to ILI patients in the primary-care setting. An open-label, multi-co...

    **ao Li, Joke Bilcke, Alike W. van der Velden, Emily Bongard in Clinical Drug Investigation (2021)

  4. Article

    Oseltamivir bij infectie door een humaan coronavirus

    In een onderzoek tijdens 3 griepseizoenen tussen 2016 en 2018 bleek dat patiënten met griepachtige klachten een dag sneller herstelden wanneer oseltamivir werd toegevoegd aan de gebruikelijke zor...

    Alike van der Velden, Herman Goossens, Daniela Cianci in Huisarts en wetenschap (2020)

  5. Article

    Open Access

    Patient understanding and acceptability of an early lung cancer diagnosis trial: a qualitative study

    The ELCID (Early Lung Cancer Investigation and Diagnosis) trial was a feasibility randomised controlled trial examining the effect on lung cancer diagnosis of lowering the threshold for referral for urgent che...

    Hayley C. Prout, Allan Barham, Emily Bongard, Rhiannon Tudor-Edwards in Trials (2018)

  6. Article

    Open Access

    Spot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis

    The use of early morning sputum samples (EMS) to diagnose tuberculosis (TB) can result in treatment delay given the need for the patient to return to the clinic with the EMS, increasing the chance of patients ...

    Michael E. Murphy, Patrick P. J. Phillips, Carl M. Mendel, Emily Bongard in BMC Medicine (2017)

  7. Article

    Open Access

    Immediate chest X-ray for patients at risk of lung cancer presenting in primary care: randomised controlled feasibility trial

    Achieving earlier stage diagnosis is one option for improving lung cancer outcomes in the United Kingdom. Patients with lung cancer typically present with symptoms to general practitioners several times before...

    Richard D Neal, Allan Barham, Emily Bongard in British Journal of Cancer (2017)

  8. Article

    Open Access

    Point of care testing for urinary tract infection in primary care (POETIC): protocol for a randomised controlled trial of the clinical and cost effectiveness of FLEXICULT™ informed management of uncomplicated UTI in primary care

    Urinary tract infections (UTI) are the most frequent bacterial infection affecting women and account for about 15% of antibiotics prescribed in primary care. However, some women with a UTI are not prescribed a...

    Janine Bates, Emma Thomas-Jones, Timothy Pickles, Nigel Kirby in BMC Family Practice (2014)

  9. Article

    Open Access

    Effects of an optimised POCT guided diagnostic and treatment strategy for symptoms of uncomplicated UTI on use of appropriate antibiotics and uptake into primary care practice

    Janine Bates, Emma Thomas-Jones, Nigel Kirby, Tim Pickles, Rhys Thomas in Trials (2013)