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Article
Open AccessPervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics
Multidimensional fitness landscapes provide insights into the molecular basis of laboratory and natural evolution. To date, such efforts usually focus on limited protein families and a single enzyme trait, wit...
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Article
Open AccessA promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion
Microbial aromatic catabolism offers a promising approach to convert lignin, a vast source of renewable carbon, into useful products. Aryl-O-demethylation is an essential biochemical reaction to ultimately catabo...
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Article
Sponge-like molecular cage for purification of fullerenes
Since fullerenes are available in macroscopic quantities from fullerene soot, large efforts have been geared toward designing efficient strategies to obtain highly pure fullerenes, which can be subsequently ap...