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Article
Open AccessCrohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrate overlap** shifts in the colonic mucosal-luminal interface microbiome
Crohn’s disease (CD) patients demonstrate distinct intestinal microbial compositions and metabolic characteristics compared to unaffected controls. However, the impact of inflammation and underlying genetic ri...
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Article
Open AccessHIV Infection is associated with compositional and functional shifts in the rectal mucosal microbiota
Regardless of infection route, the intestine is the primary site for HIV-1 infection establishment and results in significant mucosal CD4+ T lymphocyte depletion, induces an inflammatory state that propagates ...
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Article
Open AccessIntegrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships
Consistent compositional shifts in the gut microbiota are observed in IBD and other chronic intestinal disorders and may contribute to pathogenesis. The identities of microbial biomolecular mechanisms and meta...
