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  1. No Access

    Article

    Hyaluronan synthase 2 (HAS2) regulates cell phenotype and invadopodia formation in luminal-like breast cancer cells

    Although luminal breast cancer cells are typically highly cohesive epithelial cells and have low invasive ability, many eventually develop metastasis. Until now, the underlying mechanisms remain obscure. In th...

    Yumeng Sheng, Manlin Cao, Yiwen Liu, Yiqing He… in Molecular and Cellular Biochemistry (2021)

  2. No Access

    Article

    Inducible formation of leader cells driven by CD44 switching gives rise to collective invasion and metastases in luminal breast carcinomas

    Collective invasion into adjacent tissue is a hallmark of luminal breast cancer, and ~20% of these cases eventually undergo metastasis. How less aggressive luminal-like breast cancer transitions to invasive ca...

    Cuixia Yang, Manlin Cao, Yiwen Liu, Yiqing He, Yan Du, Guoliang Zhang, Feng Gao in Oncogene (2019)