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Open AccessAuthor Correction: Depletion of proteasome subunit PSMD1 induces cancer cell death via protein ubiquitination and DNA damage, irrespective of p53 status
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Open AccessDepletion of proteasome subunit PSMD1 induces cancer cell death via protein ubiquitination and DNA damage, irrespective of p53 status
Hepatocellular carcinoma (HCC) is characterized by high incidence and fatality rates worldwide. In our exploration of prognostic factors in HCC, the 26s proteasome subunit, non-ATPase 1 (PSMD1) protein emerged...
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Article
Open AccessProteomic analysis of plasma to identify novel biomarkers for intra-amniotic infection and/or inflammation in preterm premature rupture of membranes
To identify potential plasma biomarkers associated with microbial invasion of the amniotic cavity (MIAC) and/or intraamniotic inflammation (IAI) in women with preterm premature rupture of membranes (PPROM). Th...
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Article
Open AccessQuantitative proteomic analysis of human serum using tandem mass tags to predict cardiovascular risks in patients with psoriasis
Although biomarker candidates associated with psoriasis have been suggested, those for predicting the risk of cardiovascular disease (CVD) early in patients with psoriasis are lacking. We aimed to identify can...
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Article
An optical detection module-based biosensor using fortified bacterial beads for soil toxicity assessment
An optical biosensor module for soil contamination assessment is presented, employing bioluminescent bacterial bioreporters encapsulated in poly-dopamine (PD)-coated alginate microbeads. The PD-coated beads di...
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Article
Prescreening of Natural Products in Drug Discovery Using Recombinant Bioluminescent Bacteria
Strains of recombinant bioluminescent bacteria (RBB) which respond to toxic environments using various stress promoters are practical means of assessing toxicity. In previous research, RBB has proven useful fo...
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Article
Open AccessBio-hybrid inorganic microparticles derived from CO2 for highly efficient and selective removal of antibiotics
Antibiotics, which are the most important medication in human history, have brought global concerns due to their potential risk to human health and environment by accelerating the development of drug-resistant...
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Open AccessAptamer-based sandwich-type biosensors
Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detectio...
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Profiling the biological effects of wastewater samples via bioluminescent bacterial biosensors combined with estrogenic assays
Various water samples were successfully evaluated using a panel of different recombinant bioluminescent bacteria and estrogenic activity analysis. The bioluminescent bacteria strains induced by oxidative (supe...
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Advances in Aptamer Screening and Small Molecule Aptasensors
It has been 20 years since aptamer and SELEX (systematic evolution of ligands by exponential enrichment) were described independently by Andrew Ellington and Larry Gold. Based on the great advantages of aptamers,...
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Article
Conversion of carbon dioxide to oxaloacetate using integrated carbonic anhydrase and phosphoenolpyruvate carboxylase
The development and implementation of strategies for CO2 mitigation are necessary to counteract the greenhouse gas effect of carbon dioxide emissions. To demonstrate the possibility of simultaneously capturing CO
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In-situ on-fabric one-touch colorimetric detection using aptamer-conjugated gold nanoparticles
We have found that the close proximity among aptamer conjugated gold nanoparticles due to aptamer-target-aptamer binding can occur and result in a color change on fabric pads. In this study, we used aptamer-co...
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Article
Geno-Tox: Cell Array Biochip for Genotoxicity Monitoring and Classification
In vitro genotoxicity tests detect carcinogens that are thought to act primarily via a mechanism involving direct genetic damage. In this study, we constructed a Geno-Tox cell array chip for genotoxicity testi...
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Use of protein stability to develop dual luciferase toxicity bioreporter strains
This study presents a simple protocol to measure 2 promoter activities within a single culture when using both Lux and firefly luciferase (FF-Luc) reporters. To demonstrate this, 2 E. coli strains were constructe...
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Article
Global Gene Response in Saccharomyces cerevisiae Exposed to Silver Nanoparticles
Silver nanoparticles (AgNPs), exhibiting a broad size range and morphologies with highly reactive facets, which are widely applicable in real-life but not fully verified for biosafety and ecotoxicity, were sub...
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Article
A Subtractively Optimized DNA Microarray Using Non-sequenced Genomic Probes for the Detection of Food-Borne Pathogens
In this study, we present the successful detection of food-borne pathogens using randomly selected non-sequenced genomic DNA probes-based DNA microarray chips. Three food-borne pathogens, Staphylococcus aureus, S...
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Implementation of Random Bacterial Genomic DNA Microarray Chip (RBGDMC) for Screening of Dominant Bacteria in Complex Cultures
The random bacterial genomic DNA microarray chip (RBGDMC), which was fabricated using random genomic DNA fragments obtained from the fragmentation of bacterial genome by using four different pairs of restricti...
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