21 Result(s)
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Maarten L. J. Smits
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Article
Open AccessImpact of intraoperative imaging on decision-making during spine surgery: a survey among spine surgeons using simulated intraoperative images
To assess whether the intention to intraoperatively reposition pedicle screws differs when spine surgeons evaluate the same screws with 2D imaging or 3D imaging.
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Article
Open AccessLung Mean Dose Prediction in Transarterial Radioembolization (TARE): Superiority of [166Ho]-Scout Over [99mTc]MAA in a Prospective Cohort Study
Radiation pneumonitis is a serious complication of radioembolization. In holmium-166 ([166Ho]) radioembolization, the lung mean dose (LMD) can be estimated (eLMD) using a scout dose with either technetium-99 m-ma...
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Article
Open AccessHepatic Arteriography and C-Arm CT-Guided Ablation (HepACAGA) to Improve Tumor Visualization, Navigation and Margin Confirmation in Percutaneous Liver Tumor Ablation
We present a technique that combines Hepatic Arteriography with C-arm CT-Guided Ablation (HepACAGA) to improve tumor visualization, navigation and margin confirmation for percutaneous ablation of liver tumors.
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Open AccessDose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol
High dose unilobar radioembolization (also termed ‘radiation lobectomy’)—the transarterial unilobar infusion of radioactive microspheres as a means of controlling tumour growth while concomitantly inducing fut...
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Article
Balloon-Assisted Glue Embolization of an Internal Iliac Artery Aneurysm Embolization Prior to EVAR
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Article
Open AccessAssessing the accuracy of a new 3D2D registration algorithm based on a non-invasive skin marker model for navigated spine surgery
We assessed the accuracy of a new 3D2D registration algorithm to be used for navigated spine surgery and explored anatomical and radiologic parameters affecting the registration accuracy. Compared to existing ...
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Article
Open AccessStudy Protocol PROMETHEUS: Prospective Multicenter Study to Evaluate the Correlation Between Safety Margin and Local Recurrence After Thermal Ablation Using Image Co-registration in Patients with Hepatocellular Carcinoma
The primary objective is to determine the minimal ablation margin required to achieve a local recurrence rate of < 10% in patients with hepatocellular carcinoma undergoing thermal ablation. Secondary objective...
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Innovating TACE to Keep Up with the Rapidly Changing Field of Oncology
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Article
Open AccessUse of an anti-reflux catheter to improve tumor targeting for holmium-166 radioembolization—a prospective, within-patient randomized study
The objective of this study was to investigate whether the use of an anti-reflux catheter improves tumor targeting for colorectal cancer patients with unresectable, chemorefractory liver metastases (mCRC) trea...
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Article
Open AccessMode of progression after radioembolization in patients with colorectal cancer liver metastases
Radioembolization is an established treatment modality in colorectal cancer patients with liver-dominant disease in a salvage setting. Selection of patients who will benefit most is of vital importance. The ai...
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Open AccessThe superior predictive value of 166Ho-scout compared with 99mTc-macroaggregated albumin prior to 166Ho-microspheres radioembolization in patients with liver metastases
As an alternative to technetium-99m-macroaggregated albumin (99mTc-MAA), a scout dose of holmium-166 (166Ho) microspheres can be used prior to 166Ho-radioembolization. The use of identical particles for pre-treat...
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Open AccessThe Efficacy of Coil Embolization to Obtain Intrahepatic Redistribution in Radioembolization: Qualitative and Quantitative Analyses
To evaluate the efficacy of coil embolization to obtain intrahepatic redistribution in patients undergoing radioembolization.
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Article
Open AccessQuality of life in patients with liver tumors treated with holmium-166 radioembolization
Holmium-166 radioembolization is a palliative treatment option for patients with unresectable hepatic malignancies. Its influence on quality of life has not been evaluated yet. Since quality of life is very im...
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Chapter
Radioembolization
Radioembolization is a therapy during which radioactive microspheres are injected into the hepatic artery. A microcatheter is placed in the hepatic arterial vasculature, and millions of microspheres are admini...
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Article
Open AccessThe value of yttrium-90 PET/CT after hepatic radioembolization: a pictorial essay
Distribution of microspheres after radioembolization can be accurately visualized using PET/CT. In this pictorial essay, we aim to demonstrate the value of 90Y-PET/CT after radioembolization.
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Article
Open AccessRadioembolisation in Europe: A Survey Amongst CIRSE Members
Radioembolisation of liver tumours demands many choices from the physician regarding planning of treatment and subsequent follow-up.
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Article
Radioembolization Dosimetry: The Road Ahead
Methods for calculating the activity to be administered during yttrium-90 radioembolization (RE) are largely based on empirical toxicity and efficacy analyses, rather than dosimetry. At the same time, it is re...
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Article
Identifying Aberrant Hepatic Arteries Prior to Intra-arterial Radioembolization
Failing to identify aberrant hepatic arteries before radioembolization (RE) may compromise its treatment efficacy due to inadequate biodistribution of radioactive microspheres. The purpose of this study was t...
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99mTc-MAA overestimates the absorbed dose to the lungs in radioembolization: a quantitative evaluation in patients treated with 166Ho-microspheres
Radiation pneumonitis is a rare but serious complication of radioembolic therapy of liver tumours. Estimation of the mean absorbed dose to the lungs based on pretreatment diagnostic 99mTc-macroaggregated albumin ...
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Article
Open AccessMRI-based biodistribution assessment of holmium-166 poly(L-lactic acid) microspheres after radioembolisation
To demonstrate the feasibility of MRI-based assessment of the intrahepatic Ho-PLLA-MS biodistribution after radioembolisation in order to estimate the absorbed radiation dose.
