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Article
Open AccessProbabilistic tsunami forecasting for early warning
Tsunami warning centres face the challenging task of rapidly forecasting tsunami threat immediately after an earthquake, when there is high uncertainty due to data deficiency. Here we introduce Probabilistic T...
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Article
Open AccessTsunami risk management for crustal earthquakes and non-seismic sources in Italy
Destructive tsunamis are most often generated by large earthquakes occurring at subduction interfaces, but also other “atypical” sources—defined as crustal earthquakes and non-seismic sources altogether—may ca...
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Article
Hyperuricemia and Risk of Cardiovascular Outcomes: The Experience of the URRAH (Uric Acid Right for Heart Health) Project
The latest European Guidelines of Arterial Hypertension have officially introduced uric acid evaluation among the cardiovascular risk factors that should be evaluated in order to stratify patient’s risk. In fa...
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Article
Open AccessEffect of Shallow Slip Amplification Uncertainty on Probabilistic Tsunami Hazard Analysis in Subduction Zones: Use of Long-Term Balanced Stochastic Slip Models
The complexity of coseismic slip distributions influences the tsunami hazard posed by local and, to a certain extent, distant tsunami sources. Large slip concentrated in shallow patches was observed in recent ...
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Article
Open AccessA New Approximate Method for Quantifying Tsunami Maximum Inundation Height Probability
Regional and global tsunami hazard analysis requires simplified and efficient methods for estimating the tsunami inundation height and its related uncertainty. One such approach is the amplification factor (AF...
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Article
From Fish Waste to Omega-3 Concentrates in a Biorefinery Concept
The present work reports a case study for the industrialization of a biorefinery aimed at valorizing fish processing residues in order to obtain ω-3 concentrates for the nutraceutical sector. The biorefinery i...
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Article
Prevalence and control of hypertension in the general practice in Italy: updated analysis of a large database
Systematic assessment of blood pressure (BP) control rates may help to improve the clinical management of hypertension in clinical practice. This approach had limited application in Europe over the last three ...
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Article
The role of fluid migration and static stress transfer in searching connections between the May 2012 Emilia earthquakes through a fully 3D finite element modeling
On May 20 and 29, 2012, two earthquakes struck the Emilia Romagna region (Northern Italy), with similar mechanisms. The proximity in space and time between the two events required to investigate possible trigg...
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Article
Open AccessC2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro
Subjects carrying the T2238C ANP gene variant have a higher risk to suffer a stroke or myocardial infarction. The mechanisms through which T2238C/αANP exerts detrimental vascular effects need to be fully clarifie...
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Article
Blood pressure levels and control in Italy: comprehensive analysis of clinical data from 2000–2005 and 2005–2011 hypertension surveys
This analysis is aimed to determine blood pressure (BP) levels and BP control rates in a large population of hypertensive patients in Italy. Data were taken from two large and inclusive cross-sectional surveys...
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Article
Angiotensin II Receptor Blocker Neprilysin Inhibitor (ARNI): New Avenues in Cardiovascular Therapy
The burden of cardiovascular disease (CVD) is continuously and progressively raising worldwide. Essential hypertension is a major driver of cardiovascular events, including coronary artery disease, myocardial ...
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Article
Attitudes and preferences for the clinical management of hypertension and hypertension-related cardiac disease in general practice: results of the Italian Hypertension and Heart Survey
The aim of this study was to evaluate attitudes and preferences for the clinical management of hypertensive patients with cardiac organ disease, including left ventricular hypertrophy (LVH) and coronary artery...
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Article
Pulmonary embolism in pregnancy
Venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality during pregnancy or early after delivery, remaining a diagnostic and therapeutic challenge in both states. The absolute inciden...
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Article
Hypertension and kidneys: unraveling complex molecular mechanisms underlying hypertensive renal damage
Kidney damage represents a frequent event in the course of hypertension, ranging from a benign to a malignant form of nephropathy depending on several factors, that is, individual susceptibility, degree of hyp...
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Article
Prospective appraisal of the prevalence of primary aldosteronism in hypertensive patients presenting with atrial flutter or fibrillation (PAPPHY Study): rationale and study design
Primary aldosteronism (PA) is the most common endocrine form of hypertension and may carry an increased risk of atrial flutter or fibrillation (AFF). The primary goal of this multicentre cohort study is thus t...
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Article
Open AccessImpact of an open lung approach on hemodynamic parameters after cardiac surgery
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Open AccessA protective-ventilation strategy reduces pulmonary complications after cardiac surgery
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Article
Open AccessP2.02: Investigation of the Effects Induced on Endothelial Function by the Human T2238C Anp Gene Molecular Variant
The T2238C ANP gene molecular variant has been related to increased risk of cardiovascular events. In-vitro investigations of its patho-genetic mechanisms demonstrated that the 2238C allele variant induced detrim...
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Article
Smoking is associated with a high prevalence of microalbuminuria in hypertensive high-risk patients: data from I-SEARCH
Microalbuminuria (MAU) is a marker of endothelial dysfunction and a predictor of cardiovascular events. The effects of cigarette smoking on the prevalence of MAU in a high-risk population with arterial hyperte...
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Article
Antihypertensive drug therapy and blood pressure control in men and women: an international perspective
Cardiovascular death represents the single largest cause of mortality in women with 70% of deaths attributable to modifiable risk factors, such as hypertension. This analysis aims at evaluating, whether there ...
