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Article
Synthesis of Polyfunctional Oligoetherdiols Based on Allyl Glycidyl Ether
The bromination reaction of oligoetherdiol derived from allyl glycidyl ether by two procedures has been studied. It has been shown that one procedure provides monohydroxy conpounds and compounds containing no ...
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Article
Polymerization of Allyl Glycidyl Ether under the Action of the BF3–H2O Catalytic System
The polymerization of allyl glycidyl ether under the action of the BF3–H2O catalytic system is studied. It is shown by mass spectrometry that the reaction produces oligodiols with the polydispersity not exceeding...
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Article
The Effect of Secondary Structures in Peptides and Proteins on Their Chromatographic Separation
The effect of residual secondary structures in peptides and proteins on their separation is considered within the framework of the lattice model of adsorption and chromatography of macromolecules. It is shown ...
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Article
Green Chemistry of Polyurethanes: Synthesis, Functional Composition, and Reactivity of Cyclocarbonate-Containing Sunflower Oil Triglycerides—Renewable Raw Materials for New Urethanes
Epoxy- and cyclocarbonate-containing oligomers are synthesized by oxidizing sunflower oil and subsequent catalytic carbonization via reaction with carbon dioxide. Using mass spectrometry, it is shown that olig...
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Article
Disentangling of Information About the Structure of Biomolecules Based on the Decomposition and Separation of Two-Dimentional Charge Distributions of Ions
Electrospray ionization mass spectra of biomolecules typically consist of a series of multiply charged ions because of the transfer of protons or other charge carriers between ions of biomolecules and the surr...
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Article
Predictive Liquid Chromatography of Peptides Based on Hydrophilic Interactions for Mass Spectrometry-Based Proteomics
High-performance liquid chromatography (HPLC) is widely used for separation of complex peptide mixtures before mass spectrometry-based proteome analysis. In this analysis, reversed phase HPLC (RPHPLC) using no...
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Article
Applicability of the critical-chromatography concept to proteomics problems: Separation of peptides modeled by a heterogeneous rod
The problems of separation of short peptides are considered in terms of the model of rigid rod adsorption. Analytical expressions relating the retention volume to the sequence of amino-acid residues in the gra...
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Article
Cationic polymerization of glycidol
Polymerization of glycidyl alcohol induced by boron trifluoride tetrahydrofuran complex (BF3 ∙ THF) in ethylene glycol dimethyl ether (DME) and in the presence of BF3–water or BF3–glycerol catalyst system was stu...
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Article
Applicability of the critical chromatography concept to proteomic problems. II. Effect of mobile phase on the separation of peptides and proteins taking into account the amino acid sequence
The effect of parameters of a binary mobile phase (chemical properties of components, gradient profile, flow rate, and pH) on the separation of peptides and proteins is theoretically investigated using a model...
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Article
Applicability of the critical chromatography concept to proteomics problems: I. Effect of the stationary phase and the size of the chromatographic column on the dependence of the retention time of peptides and proteins on the amino acid sequence
A theoretical study of the effect of stationary phase parameters on the regularities of the separation of peptides and proteins using a model of critical chromatography BioLCCC and the Theoretical chromatography ...
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Article
Peptide identification in “shotgun” proteomics using tandem mass spectrometry: Comparison of search engine algorithms
High-throughput proteomics technologies are gaining popularity in different areas of life sciences. One of the main objectives of proteomics is characterization of the proteins in biological samples using liqu...
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Article
Green chemistry of polyurethanes: Synthesis, structure, and functionality of triglycerides of soybean oil with epoxy and cyclocarbonate groups—renewable raw materials for new urethanes
The synthesis of cyclocarbonate-containing oligomers for non-isocyanate polyurethanes via the catalytic reaction of carbon dioxide with epoxidized soybean oil has been described. It has been shown via the mass...
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Article
Inversion of chromatographic elution orders of peptides and its importance for proteomics
Inversion of the order of peptide elution in reversed-phase liquid chromatography under changing separation conditions, such as gradient slope has been considered. Using a six-protein proteolytic peptide stand...
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Article
Applicability of the critical-chromatography concept to analysis of proteins: Dependence of retention times on the sequence of amino acid residues in a chain
The BioLCCC model of the chromatographic separation of biomacromolecules, which involves the concepts of the critical chromatography of polymers, is used to describe the experimental data on the separation of ...
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Article
Use of models of biomacromolecule separation in AMT database generation for shotgun proteomics
Generation of a complex proteome database requires use of powerful analytical methods capable of following rapid changes in the proteome due to changing physiological and pathological states of the organism un...
