33 Result(s)

Article

Preparation of Cu nanoparticle colloid from a Cu ion solution by using protein surfactant

In this paper, a colloidal solution of copper nanoparticles was prepared from a Cu ion aqueous solution with the protein casein surfactant by a liquid phase reduction method at low temperature below 373K. For ...

M. Sekiguchi, K. Okawa, M. Nakahara, Y. Inaba, T. Maeda, A. Matsui… in MRS Advances (2019)

Article

A novel protein, MAPO1, that functions in apoptosis triggered by O⁶-methylguanine mispair in DNA

O⁶-Methylguanine produced in DNA induces mutation due to its ambiguous base-pairing properties during DNA replication. To suppress such an outcome, organisms possess a mechanism to eliminate cells carrying O⁶-met...

K Komori, Y Takagi, M Sanada, T-H Lim, Y Nakatsu, T Tsuzuki, M Sekiguchi… in Oncogene (2009)

Article

Comparison of the variations in the intensity of global electromagnetic resonance and ground surface temperature

We compare the dynamics of the intensity of the global electromagnetic (Schumann) resonance monitored in Japan with the global ground surface temperature (GST) over the period from November 1998 to May 2002. I...

A. P. Nickolaenko, M. Hayakawa, M. Sekiguchi… in Radiophysics and Quantum Electronics (2008)

Article

Autologous hematopoietic stem cell transplantation for refractory antiphospholipid syndrome causing myocardial necrosis

Autologous hematopoietic stem cell transplantation (HSCT) is currently being evaluated as a treatment for autoimmune diseases, including systemic lupus erythematosus (SLE), that are associated with a very seve...

N Hashimoto, T Iwasaki, M Sekiguchi, H Takatsuka, T Okamoto… in Bone Marrow Transplantation (2004)

Article

A case of cardiac sarcoidosis with advanced atrioventricular block. Failure of endomyocardial biopsy diagnosis and success in detecting

 We present a case of cardiac sarcoidosis with advanced atrioventricular (AV) block in a 45-year-old female patient. Although endomyocardial biopsy and other diagnostic findings were inconclusive, gastrocnemia...

Hiroki Kasai, Jun-ichi Suzuki, Hiroshi Imamura, Yoshikazu Yazaki… in Heart and Vessels (2003)

Article

Cerebellar anomalies in congenital murine toxoplasmosis

Gravid Nya:NYLAR mice, infected with Toxoplasma gondii on gestation day 7, experienced embryo resorptions, abortions, stillbirths, and a reduction in average litter size by one-third. Postnatally, all congenital...

W. Stahl, M. Sekiguchi, Y. Kaneda in Parasitology Research (2002)

Chapter and Conference Paper

The Third Line of Positive Allosteric Modulators for AMPA Receptors

AMPA-type glutamate receptors are important molecules in central excitatory synaptic transmission. On AMPA receptor molecules, there are allosteric modulatory sites that are different from a glutamate-binding ...

M. Sekiguchi, M. L. Mayer, K. Wada in Slow Synaptic Responses and Modulation (2000)

Article

Molecular cloning of AtMMH, an Arabidopsis thaliana ortholog of the Escherichia coli mutM gene, and analysis of functional domains of its product

We isolated and characterized cDNAs and a genomic clone encoding an Arabidopsis thaliana MutM homolog (AtMMH). AtMMH is a single-copy gene spanning about 3 kb in the nuclear genome, and comprises ten exons. The

T. Ohtsubo, O. Matsuda, K. Iba, I. Terashima… in Molecular and General Genetics MGG (1998)

Chapter and Conference Paper

Muti-Color Imaging of Clusters of Galaxies with Mosaic CCD Cameras

At present, the photometric data for clusters at z≲ 0.2 mainly come from photographic photometry. The lack of CCD data for such clusters is simply due to the fact that no CCD camera had been available until re...

S. Okamura, M. Doi, N. Kashikawa… in New Horizons from Multi-Wavelength Sky Sur… (1998)

Article

Regulation of mouse immuno-responses by a natural suppressor cell clone from bone marrow

Natural suppressor (NS) activity is mediated by several kinds of cell lineages in bone marrow. We demonstrated that a NS cell, clone 7–31, was obtained after limiting dilution with bone marrow culture suppleme...

H. Yanagië, Z. Chen, Y. Takeda, H. Sugiyama… in Research in Experimental Medicine (1997)

Article

Closed intramedullary osteotomy for rotational deformity after long bone fractures

M. Itoman, M. Sekiguchi, K. Yokoyama, I. Minamisawa in International Orthopaedics (1997)

Article

Effect ofmutY andmutM/fpg-1 mutations on starvation-associated mutation inEscherichia coli: implications for the role of 7,8-dihydro-8-oxoguanine

MutY specifies a DNA glycosylase that removes adenines unnaturally paired with various bases including oxidized derivatives of guanine, such as 7,8-dihydro-8-oxoguanine (8-oxoG). The rate of mutation in starvedEs...

B. A. Bridges, M. Sekiguchi, T. Tajiri in Molecular and General Genetics MGG (1996)

Article

Requirement for two conserved cysteine residues in the Ada protein ofEscherichia coli for transactivation of theada promoter

Cysteine residue 69 of theEscherichia coli Ada transcription factor, which accepts a methyl group from methylphosphotriester in methylated DNA, was substituted by each of 19 other amino acids. Only the mutant Ada...

A. Taketomi, Y. Nakabeppu, K. Ihara, D. J. Hart… in Molecular and General Genetics MGG (1996)

Chapter

Allograft Reconstruction of Acetabular Bone Defects Combined with Reinforcement Ring in Revision Total Hip Arthroplasty

Reconstruction of bone defects in revision total hip replacement (THR) after loosening of the prosthesis is often difficult, because of the size of the bone defect [1,2, 3]. In revision THR, a large amount of ...

M. Itoman, M. Sekiguchi in Orthopaedic Allograft Surgery (1996)

Article

A targeting model of boron neutron-capture therapy to hepatoma cellsin vivo with a boronated anti-(α-fetoprotein) monoclonal antibody

We described previously that¹⁰B atoms delivered by monoclonal antibody (mAb) exerted a cytotoxic effect on AH66 cells in a dose-dependent manner upon thermal neutron irradiationin vitro. In the present study, the...

H. Yanagië, Y. Fujii, M. Sekiguchi… in Journal of Cancer Research and Clinical On… (1994)

Article

Requirement of the Pro-Cys-His-Arg sequence for O⁶-methylguanine-DNA methyltransferase activity revealed by saturation mutagenesis with negative and positive screening

O⁶-Methylguanine-DNA methyltransferase catalyzes transfer of a methyl group from O⁶-methylguanine and O⁴-methylthymine of DNA to a cysteine residue of the enzyme protein, thereby repairing the mutagenic and carci...

K. Ibara, H. Kawate, L. -L. Chueh, H. Hayakawa… in Molecular and General Genetics MGG (1994)

Article

Pharmacokinetics of droloxifene in mice, rats, monkeys, premenopausal and postmenopausal patients

The pharmacokinetics of droloxifene have been studied in female mice, rats, monkeys, and premenopausal and postmenopausal patients. Droloxifene was rapidly and almost completely absorbed after oral dosing. The...

Y. Tanaka, M. Sekiguchi, T. Sawamoto… in European Journal of Drug Metabolism and Ph… (1994)

Chapter and Conference Paper

Automatic Morphological Classification of Galaxies

We study the performance and limitations of the morphological classification method based on luminosity concentration and mean surface brightness. In particular, the effects of the different colour bands and o...

S. Okamura, M. Doi, M. Fukugita, N. Kashikawa… in Astronomy from Wide-Field Imaging (1994)

Article

Effect of processing conditions on the characteristics of pores in hot isostatically pressed alumina

Effect of processing conditions on the characteristics of residual pores was studied with an optical microscope in hot isostatically pressed translucent alumina ceramics. Green bodies formed by isostatic press...

K. Uematsu, M. Sekiguchi, J. -Y. Kim, K. Saito, Y. Mutoh… in Journal of Materials Science (1993)