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  1. No Access

    Article

    Regulation of mouse immuno-responses by a natural suppressor cell clone from bone marrow

    Natural suppressor (NS) activity is mediated by several kinds of cell lineages in bone marrow. We demonstrated that a NS cell, clone 7–31, was obtained after limiting dilution with bone marrow culture suppleme...

    H. Yanagië, Z. Chen, Y. Takeda, H. Sugiyama… in Research in Experimental Medicine (1997)

  2. Article

    Inhibition of human pancreatic cancer growth in nude mice by boron neutron capture therapy

    Immunoliposomes were prepared by conjugating anti-carcinoembryonic antigen (CEA) monoclonal antibody with liposomes containing [10B]compound. These immunoliposomes were shown to bind selectively to human pancr...

    H Yanagië, T Tomita, H Kobayashi, Y Fujii, Y Nonaka, Y Saegusa… in British Journal of Cancer (1997)

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    Article

    A targeting model of boron neutron-capture therapy to hepatoma cellsin vivo with a boronated anti-(α-fetoprotein) monoclonal antibody

    We described previously that10B atoms delivered by monoclonal antibody (mAb) exerted a cytotoxic effect on AH66 cells in a dose-dependent manner upon thermal neutron irradiationin vitro. In the present study, the...

    H. Yanagië, Y. Fujii, M. Sekiguchi… in Journal of Cancer Research and Clinical On… (1994)

  4. No Access

    Chapter

    Targeting of Boronated Anti-Afp MoAB to Hepatoma Cells: Applications of Boronated MoAB for BNCT

    The cytotoxic effects of boron neutron capture on cancer cells were first reported by Locher 1 and Kruger 2. Cell destruction in boron neutron capture therapy (BNCT) is due to the nuclear reaction between 10B and...

    H. Yanagië, T. Takahashi, Y. Fujii, M. Sekiguchi… in Advances in Neutron Capture Therapy (1993)

  5. No Access

    Article

    Application of boronated anti-CEA immunoliposome to tumour cell growth inhibition in in vitro boron neutron capture therapy model

    An immunoliposome containing a 10B-compound has been examined as a selective drug delivery system in boron neutron-capture therapy. Liposomes, conjugated with monoclonal antibodies specific for carcinoembryoni...

    H Yanagië, T Tomita, H Kobayashi, Y Fujii, T Takahashi… in British Journal of Cancer (1991)