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  1. Article

    Open Access

    The association between satisfaction with life and anxiety symptoms among Chinese elderly: a moderated mediation analysis

    Previous studies have suggested that certain personal psychological variables (e.g., life satisfaction and cognitive function) and physical variables (e.g., body mass index [BMI]) are significantly associated ...

    Cynthia Y. Y. Lai, Lu Hua Chen, Frank H. Y. Lai, Ada W. T. Fung in BMC Geriatrics (2023)

  2. No Access

    Article

    The expression of CD86 in CD3+CD56+ NKT cells is associated with the occurrence and prognosis of sepsis-associated encephalopathy in sepsis patients: a prospective observational cohort study

    The role of CD3+CD56+ natural killer T (NKT) cells and its co-signaling molecules in patients with sepsis-associated encephalopathy (SAE) is unknown. In this prospective observational cohort study, we initially r...

    Sheng-long Chen, **ao-yu Liu, Jun-hong Huang, Lu-hua **an in Immunologic Research (2023)

  3. No Access

    Article

    Continuous electronic state regulation by tunable Mott–Schottky Heterojunction potential boosting C-C cleavage for ethanol oxidation

    The efficiency of direct ethanol fuel cells has been limited by the low performance of ethanol oxidation reaction (EOR) due to the high energy barrier for C–C bond cleavage via the C1 pathway, and thus the design...

    Zhihao Feng 冯志浩, Fengshou Yu 于丰收, Yang You 攸杨, Yaheng Wang 王亚恒 in Science China Materials (2023)

  4. Article

    Open Access

    Causal relationships of circulating amino acids with cardiovascular disease: a trans-ancestry Mendelian randomization analysis

    Epidemiological studies demonstrated that multiple amino acids (AAs) were associated with cardiovascular diseases (CVDs), but whether these associations were causal remains unclear. This study aims to investig...

    Song Hu, Zhennan Lin, Meng-** Hu, Jiang-Shan Tan in Journal of Translational Medicine (2023)

  5. Article

    Open Access

    Anomalous isotope effect on mechanical properties of single atomic layer Boron Nitride

    The ideal mechanical properties and behaviors of materials without the influence of defects are of great fundamental and engineering significance but considered inaccessible. Here, we use single-atom-thin isot...

    Alexey Falin, Haifeng Lv, Eli Janzen, James H. Edgar, Rui Zhang in Nature Communications (2023)

  6. Article

    Open Access

    Neutrophil levels upon admission for the assessment of acute pulmonary embolism with intermediate- and high-risk: an indicator of thrombosis and inflammation

    Risk prediction rules are important to establish appropriate treatment and management strategy for patients with different risk classification of pulmonary embolism (PE). Neutrophils are considered to be relat...

    Rui Peng, Weihua Yin, Fang Wang, **angfeng Cong, Bin Lu, Lu Hua in Thrombosis Journal (2023)

  7. No Access

    Article

    Toward a function realization of multi-scale modeling for lithium-ion battery based on CHAIN framework

    As the most mature portable power source, lithium-ion battery has become the mainstream of power source for electric vehicles (EVs) by virtue of its high energy density, long cycle life and relatively low cost...

    Bin Ma, Han-Qing Yu, Lu-Hua Yang, Qi Liu, Hai-Cheng **e, Si-Yan Chen in Rare Metals (2023)

  8. No Access

    Chapter and Conference Paper

    Co** with Bullying Incidents by the Narrative and Multi-modal Interaction in Virtual Reality

    Bullying poses a significant threat to students’ well-being, causing enduring psychological and physical harm. Traditional teaching falls short in preparing students to confront and counteract bullying. This s...

    Lu-Hua Ma, En-Chen Chen, Tsai-Yen Li in Advances in Visual Computing (2023)

  9. No Access

    Article

    β2-adrenergic receptor drives the metastasis and invasion of pancreatic ductal adenocarcinoma through activating Cdc42 signaling pathway

    Recent investigations indicate that β2-adrenergic receptor (β2-AR) signaling may facilitate the progression of various tumors, whose underlying mechanisms remain largely elusive. In the present study, we showe...

    Chen Gong, Baoying Hu, Haifeng Chen, Jianxin Zhu in Journal of Molecular Histology (2022)

  10. No Access

    Article

    Plasma metabolomics in the perioperative period of defect repair in patients with pulmonary arterial hypertension associated with congenital heart disease

    The quality of life and survival rates of patients with pulmonary arterial hypertension associated with congenital heart disease (CHD–PAH) have been greatly improved by defect-repair surgery and personalized t...

    Yang-yang He, Yi Yan, Ji-wang Chen, Sheng Liu, Lu Hua in Acta Pharmacologica Sinica (2022)

  11. No Access

    Article

    The long-term survival in patients with chronic thromboembolic pulmonary hypertension: experience from a single center in China

    The long-term prognosis of patients with chronic thromboembolic pulmonary hypertension (CTEPH) receiving different treatments is deserved to be analyzed in modern era of CTEPH treatment. From 2013 to 2019, a t...

    Song Hu, Jiang-Shan Tan, Sheng Liu, Ting-Ting Guo in Journal of Thrombosis and Thrombolysis (2022)

  12. Article

    Open Access

    Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

    Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...

    Huijie Bian, Zhao-Hui Zheng, Ding Wei in Signal Transduction and Targeted Therapy (2021)

  13. No Access

    Article

    Thrombus straddling a patent foramen ovale in a patient with pulmonary embolism related to essential thrombocythemia

    Jiang-Shan Tan, **n-**n Yan, **n Gao, Song Hu in International Journal of Hematology (2021)

  14. Article

    Open Access

    Numerical modeling in arterial hemodynamics incorporating fluid-structure interaction and microcirculation

    The effects of arterial wall compliance on blood flow have been revealed using fluid-structure interaction in last decades. However, microcirculation is not considered in previous researches. In fact, microcir...

    Fan He, Lu Hua, Tingting Guo in Theoretical Biology and Medical Modelling (2021)

  15. No Access

    Chapter and Conference Paper

    Optimization Analysis of Laying Length of Thin-Wall Micro-Spray Belt Under Different Slope Conditions

    To optimize the laying length of the thin-walled micro-spraying belt, the field layout way of the micro-spraying belt was considered to determine the water head distribution coefficient β as 0.55 in lateral pi...

    ** Yi Wang, Lu Hua Yang, Wan Li Gou in New Developments of IT, IoT and ICT Applie… (2021)

  16. No Access

    Article

    Discovery of oscillations above 200 keV in a black hole X-ray binary with Insight-HXMT

    Low-frequency quasiperiodic oscillations (LFQPOs) are commonly found in black hole X-ray binaries, and their origin is still under debate. The properties of LFQPOs at high energies (above 30 keV) are closely r...

    **ang Ma, Lian Tao, Shuang-Nan Zhang, Liang Zhang, Qing-Cui Bu in Nature Astronomy (2021)

  17. No Access

    Article

    Lipocalin-2 Predicts Long-Term Outcome of Normotensive Patients with Acute Pulmonary Embolism

    Normotensive patients with acute pulmonary embolism (APE) are accompanied by heterogeneously adverse events. Responding to tissue injury, lipocalin-2 (LCN-2) is elevated in experimental APE model and associate...

    Haixu Yu, Zhuohui Liu, Jie Lu, **nying Yang, **n-**n Yan in Cardiovascular Toxicology (2020)

  18. No Access

    Article

    Associating 197 Chinese herbal medicine with drug targets and diseases using the similarity ensemble approach

    Chinese herbal medicine (CHM) addresses complex diseases through polypharmacological interactions. However, systematic studies of herbal medicine pharmacology remain challenging due to the complexity of CHM in...

    Shuo Gu, Lu-hua Lai in Acta Pharmacologica Sinica (2020)

  19. No Access

    Chapter and Conference Paper

    Sniper Selection Index Measurement and Factor Weight Analysis

    There is a problem that the proportion of qualitative selection is larger than that of quantitative selection in the selection process of our army’s snipers. In this study, the methods of testing and mathemati...

    Weiming Deng, Yubo Deng, Liwei Gong, Lu Hua in Man–Machine–Environment System Engineering… (2020)

  20. No Access

    Article

    A Novel Polarization Filter Based on Photonic Crystal Fiber with a Single Au-Coated Air Hole and Semi-Hourglass Structure

    A polarization filter that has a novel photonic crystal fiber structure of semi-hourglass part and Au-coated film is proposed. We simulated the performance of the structure by the finite element method. The nu...

    **ngtao Zhao, Lu Hua, Guohui Jiang, Jirui Cheng, Qiang **ong in Plasmonics (2019)

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