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Chapter
BMPs in Inflammation
Bone morphogenetic proteins are regulators of embryonic development with multiple functions in adult organs and tissues. Here we summarize effects of BMPs outside the musculoskeletal system, focused on their r...
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Chapter
Osteogrow: A Novel Bone Graft Substitute for Orthopedic Reconstruction
Complications associated with the clinical use of BMP2 and BMP7 result from the limited understanding of their molecular mechanisms in bone remodeling. Recently, a novel BMP6-based approach has been developed ...
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Chapter
Bone Morphogenetic Protein-7 and Its Role in Acute Kidney Injury and Chronic Kidney Failure
Bone morphogenetic protein (BMP)-7 is required for embryonic kidney development, plays a functional role in the adult kidney as renal hormone for vascular and skeletal integrity, and modulates calcium and phos...