12 Result(s)
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Article
Open AccessLow-index mesoscopic surface reconstructions of Au surfaces using Bayesian force fields
Metal surfaces have long been known to reconstruct, significantly influencing their structural and catalytic properties. Many key mechanistic aspects of these subtle transformations remain poorly understood du...
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Article
Open AccessMRI can help differentiate Ménière’s disease from other menieriform diseases
It is difficult to distinguish other pathologies mimicking Ménière’s disease (MD) clinically. This study aims to investigate the differences of imaging findings and features between MD and other menieriform di...
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Article
Open AccessLearning local equivariant representations for large-scale atomistic dynamics
A simultaneously accurate and computationally efficient parametrization of the potential energy surface of molecules and materials is a long-standing goal in the natural sciences. While atom-centered message p...
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Article
Open AccessDeficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
Endocannabinoid (eCB), 2-arachidonoyl-glycerol (2-AG), the most abundant eCB in the brain, regulates diverse neural functions. Here we linked multiple homozygous loss-of-function mutations in 2-AG synthase diacyl...
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Open AccessE(3)-equivariant graph neural networks for data-efficient and accurate interatomic potentials
This work presents Neural Equivariant Interatomic Potentials (NequIP), an E(3)-equivariant neural network approach for learning interatomic potentials from ab-initio calculations for molecular dynamics simulat...
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Open AccessDifferential urine proteome analysis of a ventilator-induced lung injury rat model by label-free quantitative and parallel reaction monitoring proteomics
Urine is a promising resource for biomarker research. Therefore, the purpose of this study was to investigate potential urinary biomarkers to monitor the disease activity of ventilator-induced lung injury (VIL...
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Article
Open AccessColossal oxygen vacancy formation at a fluorite-bixbyite interface
Oxygen vacancies in complex oxides are indispensable for information and energy technologies. There are several means to create oxygen vacancies in bulk materials. However, the use of ionic interfaces to creat...
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Open AccessRevision surgery after triple semicircular canal plugging and morphologic changes of vestibular organ
This study aims to investigate the causes of vertigo relapse in patients with Meniere’s disease (MD) who had undergone triple semicircular canal plugging (TSCP) and explore the morphologic changes of vestibula...
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Open AccessUnbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice
Dopamine (DA) release in striatum is functionally segregated across a dorsolateral/ventromedial axis. Interestingly, nigrostriatal DA signaling disruption in Parkinson’s disease (PD) preferentially affects the...
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Open AccessALDH1A1 regulates postsynaptic μ–opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling
Aldehyde dehydrogenase 1A1 (ALDH1A1), a retinoic acid (RA) synthase, is selectively expressed by the nigrostriatal dopaminergic (nDA) neurons that preferentially degenerate in Parkinson’s disease (PD). ALDH1A1...
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Open AccessQuantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease
Aging is characterized by a progressive decline in the function of adult tissues which can lead to neurodegenerative disorders. However, little is known about the correlation between protein changes in the sub...
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Article
Edge dislocation slows down oxide ion diffusion in doped CeO2 by segregation of charged defects
Strained oxide thin films are of interest for accelerating oxide ion conduction in electrochemical devices. Although the effect of elastic strain has been uncovered theoretically, the effect of dislocations on...
