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Article

Heterozygous APC germline mutations impart predisposition to colorectal cancer

Familial adenomatous polyposis (FAP) is an inherited syndrome caused by a heterozygous adenomatous polyposis coli (APC) germline mutation, associated with a profound lifetime risk for colorectal cancer. While ...

Livia Preisler, Aline Habib, Guy Shapira, Liron Kuznitsov-Yanovsky… in Scientific Reports (2021)