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  1. Article

    Open Access

    Heterozygous APC germline mutations impart predisposition to colorectal cancer

    Familial adenomatous polyposis (FAP) is an inherited syndrome caused by a heterozygous adenomatous polyposis coli (APC) germline mutation, associated with a profound lifetime risk for colorectal cancer. While ...

    Livia Preisler, Aline Habib, Guy Shapira, Liron Kuznitsov-Yanovsky… in Scientific Reports (2021)

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    Modeling FXS: Human Pluripotent Stem Cells and In Vitro Neural Differentiation

    In fragile X syndrome (FXS) embryos FMRP is widely expressed during early stages of embryogenesis however it is inactivated by the end of the first trimester. In the same manner, human embryonic stem cell (hES...

    Liron Kuznitsov-Yanovsky, Yoav Mayshar, Dalit Ben-Yosef in Fragile-X Syndrome (2019)