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Article

psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation

RNA helicases remodel the spliceosome to enable pre-mRNA splicing, but their binding and mechanism of action remain poorly understood. To define helicase-RNA contacts in specific spliceosomal states, we develo...

Lisa M. Strittmatter, Charlotte Capitanchik, Andrew J. Newman… in Nature Communications (2021)