3 Result(s)
within
Charlotte Capitanchik
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Article
Open AccessPositional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP
Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale. With the increasing amounts of available data for RNA-binding proteins ...
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Article
Open AccessRNA modifications detection by comparative Nanopore direct RNA sequencing
RNA molecules undergo a vast array of chemical post-transcriptional modifications (PTMs) that can affect their structure and interaction properties. In recent years, a growing number of PTMs have been successf...
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Article
Open AccesspsiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation
RNA helicases remodel the spliceosome to enable pre-mRNA splicing, but their binding and mechanism of action remain poorly understood. To define helicase-RNA contacts in specific spliceosomal states, we develo...
