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Article
Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates
Therapeutics based on short interfering RNAs (siRNAs) delivered to hepatocytes have been approved, but new delivery solutions are needed to target additional organs. Here we show that conjugation of 2′-O-hexadecy...
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Article
Consequences of age on ischemic wound healing in rats: altered antioxidant activity and delayed wound closure
Advertisements targeted at the elderly population suggest that antioxidant therapy will reduce free radicals and promote wound healing, yet few scientific studies substantiate these claims. To better understan...
