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Article
Open AccessEnhancement of vitamin B6 production driven by omics analysis combined with fermentation optimization
Microbial engineering aims to enhance the ability of bacteria to produce valuable products, including vitamin B6 for various applications. Numerous microorganisms naturally produce vitamin B6, yet the metabolic p...
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Article
Open AccessProtein engineering and iterative multimodule optimization for vitamin B6 production in Escherichia coli
Vitamin B6 is an essential nutrient with extensive applications in the medicine, food, animal feed, and cosmetics industries. Pyridoxine (PN), the most common commercial form of vitamin B6, is currently chemicall...
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Article
A cyclin protein governs the infectious and sexual life cycles of Cryptococcus neoformans
Cell cycle is a fundamental process underlying growth and development in evolutionarily diverse organisms, including fungi. In human fungal pathogens, cell cycle control generally determines their life cycles,...
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Article
Open AccessNew aspects of microbial vitamin K2 production by expanding the product spectrum
Vitamin K2 (menaquinone, MK) is an essential lipid-soluble vitamin with critical roles in blood coagulation and bone metabolism. Chemically, the term vitamin K2 encompasses a group of small molecules that cont...
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Article
The nonextensive statistical ensembles with dual thermodynamic interpretations
The nonextensive statistical ensembles are revisited for the complex systems with long-range interactions and long-range correlations. An approximation, the value of nonextensive parameter (1 - q) is assumed to b...
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Article
An efficient method to improve the stability of submerged functionally graded cylindrical shell
An efficient method is presented to improve the stability of a submerged functionally graded (FG) cylindrical shell which is subjected to external hydrostatic pressure. To improve stability while satisfying th...
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Article
On the measurement for the speed of gravity
Newton’s law of gravity is a theory of instantaneous action at a distance. However, Einstein’s general relativity states that the speed of gravity equals the speed of light, which is finite. Therefore, it is a...
