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Article
Open AccessRegional nigral neuromelanin degeneration in asymptomatic leucine-rich repeat kinase 2 gene carrier using MRI
Asymptomatic Leucine-Rich Repeat Kinase 2 Gene (LRRK2) carriers are at risk for develo** Parkinson's disease (PD). We studied presymptomatic substantia nigra pars compacta (SNc) regional neurodegeneration in...
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Chapter and Conference Paper
A Novel Population Graph Neural Network Based on Functional Connectivity for Mental Disorders Detection
Accurate and rapid clinical confirmation of psychiatric disorders based on imaging, symptom and scale data has long been difficult. Graph neural networks have received increasing attention in recent years due ...
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Article
The association of self-efficacy with well-being and ill-being: The possible mediator of co** and moderator of gender
Self-efficacy and co** strategies have been demonstrated to predict well-being and ill-being, respectively. However, the relationships among self-efficacy, co**, and well-being/ill-being have been less cle...
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Article
Elevation-dependent tree growth response to recent warming and drought on eastern Tibetan Plateau
Increasing warming and drought intensity and frequency have led to profound impacts on forest ecosystems around the world. However, few studies have assessed the impacts of climate change on the alpine forest...
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Article
Open AccessDisruption of locus coeruleus-related functional networks in Parkinson’s disease
Locus coeruleus (LC) is severely affected in Parkinson’s Disease (PD). However, alterations in LC-related resting-state networks (RSNs) in PD remain unclear. We used resting-state functional MRI to investigate...
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Article
Influence of monsoon anomalies on intra-annual density fluctuations of Chinese pine in the Loess Plateau
In the past few decades, the East Asian summer monsoon (EASM) has experienced an unprecedented weakening, exacerbating drought in northern China, especially in the monsoon margin area. Improving our understand...
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Article
Open AccessAuthor Correction: Common and distinct roles of amygdala subregional functional connectivity in non-motor symptoms of Parkinson’s disease
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Article
Open AccessCommon and distinct roles of amygdala subregional functional connectivity in non-motor symptoms of Parkinson’s disease
Neuroimaging studies suggest a pivotal role of amygdala dysfunction in non-motor symptoms (NMS) of Parkinson’s disease (PD). However, the relationship between amygdala subregions (the centromedial (CMA), basol...
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Article
Divergent responses of Qinghai spruce (Picea crassifolia) to recent warming along elevational gradients in the central Qilian Mountains, Northwest China
Understanding the radial growth trends of trees and their response to recent warming along elevation gradients is crucial for assessing how forests will be impacted by future climate change. Here, we collected...
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Article
Brønsted acid-enhanced direct hydrogen atom transfer photocatalysis for selective functionalization of unactivated C(sp3)–H bonds
The manipulation of unactivated aliphatic C–H bonds remains one of the most challenging tasks in synthetic chemistry. Direct hydrogen atom transfer (HAT) photocatalysis is an appealing approach to this goal. H...
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Article
Open AccessConvolutional neural network optimizes the application of diffusion kurtosis imaging in Parkinson’s disease
The literature regarding the use of diffusion-tensor imaging-derived metrics in the evaluation of Parkinson’s disease (PD) is controversial. This study attempted to assess the feasibility of a deep-learning-ba...
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Article
Open AccessAtlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
To gain mechanistic insights into the functions and developmental dynamics of tumor-infiltrated immune cells, especially B-lymphocytes, here we combine single-cell RNA-sequencing and antigen receptor lineage a...
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Article
Long non-coding RNA HCG18 promotes M1 macrophage polarization through regulating the miR-146a/TRAF6 axis, facilitating the progression of diabetic peripheral neuropathy
Diabetic peripheral neuropathy (DPN) is one of the most important complications in diabetes mellitus (DM), which has been reported to be modulated by long non-coding RNAs (lncRNAs). The purpose of the current ...
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Article
Open AccessCircSMYD4 regulates proliferation, migration and apoptosis of hepatocellular carcinoma cells by sponging miR-584-5p
There is evidence that circSMYD4 is differentially expressed in hepatocellular carcinoma (HCC), but its mechanism of action remains unclear. Therefore, this study aimed to explore the role of circSMYD4 in the ...
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Article
Correction to: DNA ty** from skeletal remains: a comparison between capillary electrophoresis and massively parallel sequencing platforms
The name of an author was misspelled. The correct spelling is “Linlin Gao” instead of Linin Gao.
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Article
DNA ty** from skeletal remains: a comparison between capillary electrophoresis and massively parallel sequencing platforms
Skeletal remains encountered frequently in forensic applications are a challenging specimen, since their DNA is usually degraded due to harsh conditions, limiting the utilization of skeletal DNA. Forensic scie...
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Article
Open AccessEndophytic fungal community in grape is correlated to foliar age and domestication
The composition of endophytic communities has been shown to depend on grape genotypes and viticultural managements in leaves, stems, and berries of grape, but there have been relatively few reports exploring f...
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Article
Clinical features and visual prognostic indicators after vitrectomy for Terson syndrome
To determine clinical characteristics and identify factors associated with better visual outcomes in patients who had vitrectomy for vitreous haemorrhage (VH) associated with Terson syndrome (TS).
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Article
Open AccessPKCζ facilitates lymphatic metastatic spread of prostate cancer cells in a mice xenograft model
Prostate cancer disseminates primarily into the adjacent lymph nodes, which is related to a poor outcome. Atypical protein kinase C ζ (PKCζ) is highly expressed in aggressive prostate cancer and correlates wit...
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Article
Difference of acute dissociation and 1-day culture on the electrophysiological properties of rat dorsal root ganglion neurons
The dissociated dorsal root ganglion (DRG) neurons with or without culture were widely used for investigation of their electrophysiological properties. The culture procedures, however, may alter the properties...