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Article
Open AccessAssociation of chemerin mRNA expression in human epicardial adipose tissue with coronary atherosclerosis
Growing evidence suggests that epicardial adipose tissue (EAT) may play a key role in the pathogenesis and development of coronary artery disease (CAD) by producing several inflammatory adipokines. Chemerin, a...
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Article
Developmental expression changes of the genes involved in IGFI signaling pathway in longissimus dorsi muscle of Tongcheng and Yorkshire pigs during postnatal growth
IGFI signaling pathway is sufficient to regulate myofibre hypertrophy postnatally, which is associated with muscle mass in economically livestock. In the present study, we drafted the developmental expression ...
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Article
Molecular and functional characterization of glycogen synthase in the porcine satellite cells under insulin treatment
Glycogen synthase (GS) catalyzes the key step of glycogen synthesis and plays an important role in glycogen metabolism in liver and muscle. In this study, we cloned the cDNA and promoter sequences of porcine g...
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Article
Molecular characterization, expression patterns and subcellular localization of Myotrophin (MTPN) gene in porcine skeletal muscle
Myotrophin (MTPN) is an effective growth factor in promoting skeletal muscle growth in vitro and vivo and has been purified from porcine skeletal muscle. However, in pigs, the information on MTPN gene is very lim...
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Article
Whole-body vibration and resistance exercise prevent long-term hindlimb unloading-induced bone loss: independent and interactive effects
Skeletal unloading induced by disuse or immobilization causes a decrease in bone mass and strength. We investigated the relationship between whole-body vibration (WBV) and resistance exercise (RE) in preventin...
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Article
Identification of porcine glycogen synthase kinase 3α (GSK-3α) gene and its association with carcass traits
GSK-3 plays an important role on numerous cellular processes involved in the regulation of embryonic development, protein synthesis, glycogen metabolism, inflammatory, mitosis and apoptosis. In this study, we ...
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Article
Molecular characterization and different expression patterns of the FABP gene family during goat skeletal muscle development
The FABP (adipocyte fatty acid-binding protein) genes play an important role in intracellular fatty acid transport and considered to be candidate genes for fatness traits in domestic animal. In this study, we ...
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Article
Open AccessExpression patterns of TRα and CRABPII genes in Chinese cashmere goat skin during prenatal development
The physiologic characteristics of the cashmere trait and many of the differentially expressed genes relevant to hair cycling have been extensively studied, whereas genes involved in the prenatal development o...
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Article
Open AccessDNA methylation Landscape of body size variation in sheep
Sub-populations of Chinese Mongolian sheep exhibit significant variance in body mass. In the present study, we sequenced the whole genome DNA methylation in these breeds to detect whether DNA methylation plays...
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Chapter and Conference Paper
A Deep Learning Approach for Question Answering Over Knowledge Base
With the increase of the scale of the knowledge base, it’s important to answer question over knowledge base. In this paper, we will introduce a method to extract answers from Chinese knowledge base for Chinese...
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Article
Delta-like 1 homolog in Capra hircus: molecular characteristics, expression pattern and phylogeny
To research the molecular characteristics, expression pattern and phylogeny of the Delta-like 1 homolog gene (Dlk1) in goats. Dlk1 transcripts were identified in the Jianyang Da’er goats by reverse-transcription ...
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Article
Open AccessGenome-wide identification and characterization of long non-coding RNAs in developmental skeletal muscle of fetal goat
Long non-coding RNAs (lncRNAs) have been studied extensively over the past few years. Large numbers of lncRNAs have been identified in mouse, rat, and human, and some of them have been shown to play important ...
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Article
Transcriptional regulation of pig GYS1 gene by glycogen synthase kinase 3β (GSK3β)
Glycogen synthase kinase 3β (GSK3β) is a ubiquitous serine/threonine kinase and has important roles in glycogen metabolism biosynthesis. Studies have revealed that GSK3β can directly regulate the glycogen synt...
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Article
Open AccessThe prevalence and risk factors of preterm small-for-gestational-age infants: a population-based retrospective cohort study in rural Chinese population
Preterm birth and small for gestational age (SGA) are strong indicators of neonatal adverse outcomes. With the growing importance of preterm SGA infants, we aim to evaluate the prevalence and risk factors for ...
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Chapter and Conference Paper
Beyond Pivot for Extracting Chinese Paraphrases
Paraphrasing is a critical issue in many Natural Language Processing (NLP) applications. The traditional Pivot-based methods of extracting paraphrases require a large-scale bilingual parallel corpus. The quali...
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Article
Dynamic transcriptomic analysis in hircine longissimus dorsi muscle from fetal to neonatal development stages
Muscle growth and development from fetal to neonatal stages consist of a series of delicately regulated and orchestrated changes in expression of genes. In this study, we performed whole transcriptome profilin...
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Article
Open AccessThe application of intraoperative ankle dislocation approach in the treatment of the unstable trimalleolar fractures involving posterior ankle comminuted fracture: a retrospective cohort study
The aim of this study was to introduce a novel intraoperative lateral ankle dislocation approach during surgical treatment for patients with unstable trimalleolar fractures involving posterior ankle comminuted...
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Article
Open AccessWhole-genome sequencing reveals selection signatures associated with important traits in six goat breeds
Comparative population genomics analysis is an effective approach to identify selection signatures in farm animals. In this study, we systematically investigated the selection signatures in six phenotypically ...
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Article
Open AccessBoth maternal and paternal risk factors for term singleton low birthweight infants in rural Chinese population: a population-based, retrospective cohort study
No large population-based study has focused on both maternal paternal risk factors for low birthweight (LBW) in China. We aimed to identify parental risk factors associated with LBW.A population-based, retrosp...
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Article
Open AccessHeight at three months can indicate overweight at two years in catch-up growth of small for gestational age infants
This study aimed to find an indicator at three months to predict overweight and short stature at two years in small for gestational age (SGA) infants. A total of 468 SGA infants and 4642 appropriate for gestat...