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Article
Open AccessIntraperitoneal versus intranasal administration of lipopolysaccharide in causing sepsis severity in a murine model: a preliminary comparison
Community-acquired respiratory infection is the commonest cause of sepsis presenting to emergency departments. Yet current experimental animal models simulate peritoneal sepsis with intraperitoneal (I.P.) injecti...
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Article
Open AccessApplying artificial neural network in predicting sepsis mortality in the emergency department based on clinical features and complete blood count parameters
A complete blood count (CBC) is routinely ordered for emergency department (ED) patients with infections. Certain parameters, such as the neutrophil-to-lymphocyte ratio (NLR), might have prognostic value. We a...
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Article
Open AccessFrontal cortex activity during the production of diverse social communication calls in marmoset monkeys
Vocal communication is essential for social behaviors in humans and non-human primates. While the frontal cortex is crucial to human speech production, its role in vocal production in non-human primates has lo...
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Article
Open AccessMetabolomics-guided identification of compounds with antibacterial and antioxidant activities from Polygonatum sibiricum-derived endophytic fungi
Infections caused by multidrug resistant bacterial pathogens have been recognized as major global healthcare threat to medicinal, agricultural and pharmaceutical industries by World Health Organization. In thi...
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Article
Thermal enhancement of gelatin hydrogels for a multimodal sensor and self-powered triboelectric nanogenerator at low temperatures
Conductive hydrogels always suffer from weak mechanical capabilities, low adhesion, and lack of antifreeze performance, which seriously restrict their application in flexible wearable devices at low temperatur...
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Article
Open AccessBioengineering of air-filled protein nanoparticles by genetic and chemical functionalization
Various bacteria and archaea, including halophilic archaeon Halobacterium sp. NRC-1 produce gas vesicle nanoparticles (GVNPs), a unique class of stable, air-filled intracellular proteinaceous nanostructures. GVNP...
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Article
Open AccessA cross-sectional study of the endorsement proportion of reporting guidelines in 1039 Chinese medical journals
Reporting quality is a critical issue in health sciences. Adopting the reporting guidelines has been approved to be an effective way of enhancing the reporting quality and transparency of clinical research. In...
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Chapter and Conference Paper
Are There Any Winners on Both Sides of the Trade Conflict: Evidence from China and U.S.
The trade conflict has imposed severe hits on China’s and American financial markets, which is reflected by the yield of five indexes. This paper assesses the impact of tariffs on five indexes, which include S...
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Article
Efficacy, safety, and prognostic factors of drug-eluting beads transarterial chemoembolization using CalliSpheres in treating huge hepatocellular carcinoma patients
The treatment of huge hepatocellular carcinoma (HCC) is still challengeable due to its deteriorative heterogeneity, for which conventional transarterial chemoembolization (TACE) is proposed as an efficient the...
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Article
Mild hyperthermia synergized chemotherapy by Bi2Se3/MoSe2 nanosaucers for cancer treatment with negligible thermal resistance
Harsh photothermal temperatures (> 50 °C) caused heating damage to the normal tissues and induced thermal resistance in cancer cells, which significantly limited the safety and efficacy of photothermal therapy...
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Article
Open AccessVertical transmission of the gut microbiota influences glucose metabolism in offspring of mice with hyperglycaemia in pregnancy
Hyperglycaemia in pregnancy (HIP) is a common metabolic disorder that not only poses risks to maternal health but also associates with an increased risk of diabetes among offspring. Vertical transmission of mi...
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Article
Generation of long-lived charges in organic semiconductor heterojunction nanoparticles for efficient photocatalytic hydrogen evolution
Organic semiconductor photocatalysts for the production of solar fuels are attractive as they can be synthetically tuned to absorb visible light while simultaneously retaining suitable energy levels to drive a...
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Article
Necroptosis-elicited host immunity: GOx-loaded MoS2 nanocatalysts for self-amplified chemodynamic immunotherapy
Nanoparticles induced potent antitumor immunotherapy plays a significant role for enhancing conventional therapeutic effectiveness. However, revealing the pathway of how nanoagents themselves trigger the host ...
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Article
Open AccessRapid assembly of colorless antimicrobial and anti-odor coatings from polyphenols and silver
The development of antimicrobial fabrics and textiles that can sustainably inhibit a broad spectrum of microbes is crucial for protecting against pathogens in various environments. However, engineering antimic...
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Article
Crosstalk between PC12 cells and endothelial cells in an artificial neurovascular niche constructed by a dual-functionalized self-assembling peptide nanofiber hydrogel
The coordination between neurogenesis and angiogenesis plays an important role in nerve tissue development and regeneration. Recently, using bioactive materials to drive neurogenic and angiogenic responses has...
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Article
Charge prediction modeling with interpretation enhancement driven by double-layer criminal system
With the rapid development of artificial intelligence and the increasing demand for legal intelligence, using AI methods to predict legal judgments has become a hot spot in recent years. Charge prediction is o...
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Article
Open AccessEfficacy and Safety of Platelet-Rich Plasma in Melasma: A Systematic Review and Meta-Analysis
Melasma is a chronic and recurrent skin problem for which an effective therapy is currently lacking. Platelet-rich plasma (PRP) has recently emerged as a novel treatment for melasma, but to date there has been...
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Article
Hypolimnetic anoxia and sediment oxygen demand during stratification in a drinking water reservoir
Although hypolimnetic anoxia is a common occurrence in deep lakes and reservoirs, understanding the processes of oxygen depletion in water columns and sediment is challenging. This study investigates oxygen de...
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Article
Open AccessSingle particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution
The fast development of single-particle cryogenic electron microscopy (cryo-EM) has made it more feasible to obtain the 3D structure of well-behaved macromolecules with a molecular weight higher than 300 kDa a...
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Article
Radiomics based on multicontrast MRI can precisely differentiate among glioma subtypes and predict tumour-proliferative behaviour
To explore the feasibility and diagnostic performance of radiomics based on anatomical, diffusion and perfusion MRI in differentiating among glioma subtypes and predicting tumour proliferation.
