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Article
Open AccessRNA silencing and HIV: A hypothesis for the etiology of the severe combined immunodeficiency induced by the virus
A novel intrinsic HIV-1 antisense gene was previously described with RNA initiating from the region of an HIV-1 antisense initiator promoter element (HIVaINR). The antisense RNA is exactly complementary to HIV...
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Article
Open AccessHuman Immunodeficiency Virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products
While viruses have long been shown to capitalize on their limited genomic size by utilizing both strands of DNA or complementary DNA/RNA intermediates to code for viral proteins, it has been assumed that human...
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Chapter
Biological Activities of HIV-Specific Peptides
Infection with different viruses may produce immunologic dysfunctions in the host ranging from immunodeficiency states to autoimmune disorders. Generally it was assumed that these actions were related to the d...