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Article
Open AccessEndometrial Elasticity is an Ultrasound Marker for Predicting Clinical Pregnancy Outcomes after Embryo Transfer
Endometrial elasticity is a potential new marker for assessing endometrial receptivity and pregnancy outcomes based on endometrial thickness and type. Currently, little research has been conducted on the elast...
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Article
Open AccessPotential causal associations between leisure sedentary behaviors, physical activity, sleep traits, and myopia: a Mendelian randomization study
Myopia is the most prevalent refractive error and a growing global health concern that significantly affects visual function. Researchers have recently emphasized considerably on the influence of lifestyle on ...
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Article
Recent development of three-dimension printed graphene oxide and MXene-based energy storage devices
The research for three-dimension (3D) printing carbon and carbide energy storage devices has attracted widespread exploration interests. Being designable in structure and materials, graphene oxide (GO) and MXe...
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Article
Don’t worry about noisy labels in soft shadow detection
Soft shadow is harder to detect than hard shadow as its complex characteristics (i.e., low-contrast, irregular shape, and ambiguous shadow boundaries). To improve the detecting capacity of these images, in thi...
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Article
Open AccessSpecific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder
Autistic traits (ATs) are frequently reported in children with Attention-Deficit/Hyperactivity Disorder (ADHD). This study aimed to examine ATs in children with ADHD from both behavioral and neuroimaging persp...
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Article
Clinical epidemiology and disease burden of bronchiolitis in hospitalized children in China: a national cross-sectional study
Bronchiolitis is a common acute lower respiratory tract infection (ALRTI) and the most frequent cause of hospitalization of infants and young children with ALRTI. Respiratory syncytial virus is the main pathog...
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Article
Single-center phase 2 study of PD-1 inhibitor combined with DNA hypomethylation agent + CAG regimen in patients with relapsed/refractory acute myeloid leukemia
Anti-PD-1 monotherapy had limited clinical efficacy in relapsed/refractory (r/r) AML patients with higher PD-1 and PD-L1 expression. Hence, we investigated the efficacy and safety of PD-1 inhibitor with DNA hy...
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Article
Open AccessSyncope as the initial symptom in a patient with nasopharyngeal carcinoma: a case report
A high prevalence of nasopharyngeal carcinoma (NPC) has been found in China, but it rarely occurs with syncope. Studies have demonstrated that syncope due to NPC may be related to carotid sinus syndrome, gloss...
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Article
Synthesis and biological evaluation of new thiazolyl-urea derivatives as potential dual C-RAF/FLT3 inhibitors
Based on a structure-activity relationship of compounds such as Sorafenib and Quizartinib, a series of thiazol-urea derivatives containing hydrophilic side moiety were designed and synthesized, aiming to impro...
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Article
Open AccessCorrection to: BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis
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Open AccessBMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis
Age-related osteoporosis is characterized by the accumulation of senescent osteoblastic cells in bone microenvironment and significantly reduced osteogenic differentiation. Clearing of the senescent cells is h...
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Open AccessApplications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review
Scutellaria baicalensis Georgi. (SB) is a common heat-clearing medicine in traditional Chinese medicine (TCM). It has been used for thousands of years in China and its neighboring countries. Clinically, it is mos...
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Article
Short-lived AIM2 Inflammasome Activation Relates to Chronic MCMV Infection in BALB/c Mice
Absent in melanoma 2 (AIM2) inflammasome is a crucial link bridging the innate host defense and the subsequent adaptive immunity when activated by exogenous double stranded DNA (dsDNA). Through establishing mo...
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Open AccessMid- to long-term results of total disc replacement for lumbar degenerative disc disease: a systematic review
Lumbar total disc replacement (TDR) has shown satisfactory clinical outcomes with few complications and reoperations at short-term follow-up, but the mid- to long-term results are not clear.
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Article
Maternal Murine Cytomegalovirus Infection during Pregnancy Up-regulates the Gene Expression of Toll-like Receptor 2 and 4 in Placenta
Increasing evidence has revealed that maternal cytomegalovirus (CMV) infection may be associated with neurodevelopmental disorders in offspring. Potential relevance between the placental inflammation and CMV-r...
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Article
Response of the wheat rhizosphere soil nematode community in wheat/walnut intercrop** system in **njiang, Northwest China
Intercrop** Persian walnut (Juglans regia L.) and wheat (Triticum aestivum L.) have been widely applied in the **njiang Uygur Autonomous Region in Northwest China as a means of reducing soil and water losses an...
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Charactering the metabolism of cryptotanshinone by human P450 enzymes and uridine diphosphate glucuronosyltransferases in vitro
Cryptotanshinone (CT) is the main active component in the root of Salvia miltiorrhiza Bunge (SMB) that displays antibacterial, anti-inflammatory and anticancer activities. In this study, we characterized phase I ...
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Article
Weighted Co-Training for Cross-Domain Image Sentiment Classification
Image sentiment classification, which aims to predict the polarities of sentiments conveyed by the images, has gained a lot of attention. Most existing methods address this problem by training a general classi...
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Article
CNOP-based sensitive areas identification for tropical cyclone adaptive observations with PCAGA method
In this paper, conditional nonlinear optimal perturbation (CNOP) was investigated to identify sensitive areas for tropical cyclone adaptive observations with principal component analysis based genetic algorith...
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Article
Open AccessInfluence of the lateral pterygoid muscle on traumatic temporomandibular joint bony ankylosis
The pathogenesis of traumatic TMJ ankylosis remains unclear. This study aimed to verify the role of the lateral pterygoid muscle in the pathogenesis of traumatic temporomandibular joint (TMJ) bony ankylosis.
