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    Article

    Ventral subiculum promotes wakefulness through several pathways in male mice

    The ventral subiculum (vSUB), the major output structure of the hippocampal formation, regulates motivation, stress integration, and anxiety-like behaviors that rely on heightened arousal. However, the roles a...

    Xue-Fen Zhang, Yi-Dan Li, Yue Li, Ying Li, Dan Xu, Lin-Lin Bi in Neuropsychopharmacology (2024)

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    PV network plasticity mediated by neuregulin1-ErbB4 signalling controls fear extinction

    Neuroplasticity in the medial prefrontal cortex (mPFC) is essential for fear extinction, the process of which forms the basis of the general therapeutic process used to treat human fear disorders. However, the...

    Yi-Hua Chen, Neng-Yuan Hu, Ding-Yu Wu, Lin-Lin Bi, Zheng-Yi Luo in Molecular Psychiatry (2022)

  3. Article

    Amygdala NRG1–ErbB4 Is Critical for the Modulation of Anxiety-Like Behaviors

    Anxiety disorder is related to the pathophysiology of psychiatric diseases, including major depression, substance abuse, and schizophrenia. The amygdala is important for manifestation and modulation of anxiety...

    Lin-Lin Bi, **ang-Dong Sun, Jie Zhang, Yi-Sheng Lu, Yi-Hua Chen in Neuropsychopharmacology (2015)