Skip to main content

8 Result(s)

within Lin-Lin Bi Remove this filter

and

  1. No Access

    Article

    Ventral subiculum promotes wakefulness through several pathways in male mice

    The ventral subiculum (vSUB), the major output structure of the hippocampal formation, regulates motivation, stress integration, and anxiety-like behaviors that rely on heightened arousal. However, the roles a...

    Xue-Fen Zhang, Yi-Dan Li, Yue Li, Ying Li, Dan Xu, Lin-Lin Bi… in Neuropsychopharmacology (2024)

  2. No Access

    Article

    PV network plasticity mediated by neuregulin1-ErbB4 signalling controls fear extinction

    Neuroplasticity in the medial prefrontal cortex (mPFC) is essential for fear extinction, the process of which forms the basis of the general therapeutic process used to treat human fear disorders. However, the...

    Yi-Hua Chen, Neng-Yuan Hu, Ding-Yu Wu, Lin-Lin Bi, Zheng-Yi Luo… in Molecular Psychiatry (2022)

  3. No Access

    Article

    Optogenetic Long-Term Depression Induction in the PVT-CeL Circuitry Mediates Decreased Fear Memory

    The dysregulation of fear learning and abnormal activities of cerebral networks may contribute to the etiologies of anxiety disorders. Although it has been proposed that decreased activity in the paraventricul...

    Ming Chen, Lin-lin Bi in Molecular Neurobiology (2019)

  4. Article

    Open Access

    Amygdalar Endothelin-1 Regulates Pyramidal Neuron Excitability and Affects Anxiety

    An abnormal neuronal activity in the amygdala is involved in the pathogenesis of anxiety disorders. However, little is known about the mechanisms. High-anxiety mice and low-anxiety mice, representing the innat...

    Ming Chen, Huan-huan Yan, Shu Shu, Lei Pei, Long-kai Zang, Yu Fu… in Scientific Reports (2017)

    Download PDF (4037 KB) View Article

  5. No Access

    Article

    Infralimbic Endothelin1 Is Critical for the Modulation of Anxiety-Like Behaviors

    Endothelin1 (ET1) is a potent vasoconstrictor that is also known to be a neuropeptide that is involved in neural circuits. We examined the role of ET1 that has been implicated in the anxiogenic process. We fou...

    Lin-Lin Bi, Ming Chen, Lei Pei, Shu Shu, Hui-Juan **… in Molecular Neurobiology (2016)

  6. Article

    Amygdala NRG1–ErbB4 Is Critical for the Modulation of Anxiety-Like Behaviors

    Anxiety disorder is related to the pathophysiology of psychiatric diseases, including major depression, substance abuse, and schizophrenia. The amygdala is important for manifestation and modulation of anxiety...

    Lin-Lin Bi, **ang-Dong Sun, Jie Zhang, Yi-Sheng Lu, Yi-Hua Chen… in Neuropsychopharmacology (2015)

    Download PDF (1384 KB) View Article

  7. No Access

    Article

    Enrichment of cardiac differentiation by a large starting number of embryonic stem cells in embryoid bodies is mediated by the Wnt11-JNK pathway

    Embryoid bodies (EBs) with large starting numbers of embryonic stem cells (ESCs) have a greater degree of cardiac differentiation than from low numbers of EBs. However, the biological roles of signaling molecu...

    Ming Chen, Cheng Qian, Lin-Lin Bi, Fang Zhao, Guang-Yu Zhang… in Biotechnology Letters (2015)

  8. No Access

    Article

    Time-dependent regulation of neuregulin-1β/ErbB/ERK pathways in cardiac differentiation of mouse embryonic stem cells

    Neuregulin-1β (NRG-1β)/ErbB signaling plays crucial roles in the cardiac differentiation of mouse embryonic stem cells (ESCs), but its roles and the underlying mechanisms in cardiac differentiation are incompl...

    Ming Chen, Lin-Lin Bi, Zhi-Quan Wang, Fang Zhao… in Molecular and Cellular Biochemistry (2013)