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Article
Open AccessGenome-wide profiling of angiogenic cis-regulatory elements unravels cis-regulatory SNPs for vascular abnormality
Angiogenesis is extensively involved in embryonic development and requires complex regulation networks, whose defects can cause a variety of vascular abnormalities. Cis-regulatory elements control gene expression...
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Article
Open AccessDapagliflozin promotes browning of white adipose tissue through the FGFR1-LKB1-AMPK signaling pathway
Obesity is associated with a wide variety of metabolic disorders that impose significant burdens on patients and society. The “browning” phenomenon in white adipose tissue (WAT) has emerged as a promising ther...
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Article
Synergistic action of hygroscopic and coalescing of biomass-based polymer in radioactive aerosol sedimentation
Radioactive aerosols produced by nuclear accidents and decommissioning of nuclear power plants would cause tremendous radioactive damage to the environment and human body. The development of a radioactive aero...
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Article
BiLSTM-TANet: an adaptive diverse scenes model with context embeddings for few-shot learning
Few-shot learning is a critical task in computer vision processing that helps reduce deep learning’s reliance on large datasets. This paper aims to establish a few-shot learning network that is adaptive to div...
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Article
Open AccessClinical, genetic profile and therapy evaluation of 11 Chinese pediatric patients with Fanconi-Bickel syndrome
Fanconi-Bickel syndrome (FBS) is a rare autosomal recessive disorder characterized by impaired glucose and galactose utilization as well as proximal renal tubular dysfunction.
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Article
The chemical recognition of hydrogen fluoride via B24N24 nanocage: quantum chemical approach
Ab initio calculations were employed in this investigation to scrutinize the adsorption characteristics of a linear chain (HF)n on a BN nanocage (B24N24), wherein the chain lengths varied (n = 1, 2, 3, and 4). Th...
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Article
Open AccessLate-onset cblC defect: clinical, biochemical and molecular analysis
cblC defect is the most common type of methylmalonic acidemia in China. Patients with late-onset form (>1 year) are often misdiagnosed due to heterogeneous symptoms. This study aimed to describe clinical chara...
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Article
Open AccessClinical and genetic characteristics of 42 Chinese paediatric patients with X-linked adrenal hypoplasia congenita
X-linked adrenal hypoplasia congenita (AHC) is a rare disorder characterized by primary adrenal insufficiency (PAI) and hypogonadotropic hypogonadism (HH), with limited clinical and genetic characterization.
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Article
Bioavailability and regional transport of PM2.5 during heavy haze episode in typical coal city site of Fenwei Plain, China
Despite the decrease in anthropogenic emissions, haze episodes were still frequent in the Fenwei Plain, which was identified as one of the three key areas for air pollution control. Herein, PM2.5 samples were col...
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Article
Monitoring of COS, SO2, H2S, and CS2 gases by Al24P24 nanoclusters: a DFT inspection
Through utilizing density functional theory (DFT), the current work investigates the potential uses of Al24P24 fullerene for detecting CS2, H2S, SO2, and COS. The interaction order for the stability of these gase...
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Article
Open AccessClinical, biochemical, and genetic analysis of 28 Chinese patients with holocarboxylase synthetase deficiency
This study aimed to describe the clinical, biochemical, and molecular characteristics of Chinese patients with holocarboxylase synthetase (HLCS) deficiency, and to investigate the mutation spectrum of HCLS def...
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Article
Open AccessPaediatric sepsis-associated encephalopathy (SAE): a comprehensive review
Sepsis-associated encephalopathy (SAE) is one of the most common types of organ dysfunction without overt central nervous system (CNS) infection. It is associated with higher mortality, low quality of life, an...
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Article
Open AccessEffects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy
Sepsis-associated encephalopathy (SAE) is one of the most common types of sepsis-related organ dysfunction without overt central nervous system (CNS) infection. It is associated with higher mortality, low qual...
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Article
Open AccessScreening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats
microRNA (miRNA) is a type of endogenous short-chain non-coding RNA with regulatory function found in eukaryotes, which is involved in the regulation of a variety of cellular and biological processes. However,...
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Article
Biodegradable antifreeze foam stabilized by lauryl alcohol for radioactive surface decontamination
Conventional water-based detergents cannot remove radioactive contamination on the surface below 0 °C. In order to solve this problem, a biodegradable antifreeze foam, containing the antifreeze, the chelating ...
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Article
Open AccessNon-linear relationship of gamma-glutamyl transpeptidase to lymphocyte count ratio with the recurrence of hepatocellular carcinoma with staging I–II: a retrospective cohort study
High recurrence rate was a major factor for the poor postoperative prognosis of hepatocellular carcinoma (HCC) patients. The present study was intended to evaluate the association of gamma-glutamyl transpeptid...
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Article
Gene expression profiles in the brain of phenylketonuria mouse model reversed by the low phenylalanine diet therapy
To gain insight into the potential protective mechanisms of low phenylalanine diet (LPD) in phenylketonuria (PKU), gene expression profiles were studied in the cerebral cortex and hippocampus of a PKU mouse mo...
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Article
Movie Recommendation System for Educational Purposes Based on Field-Aware Factorization Machine
With rich resources, movies have been applied as instructional media in the domain of education, such as fields of Second/Foreign Language Leaning, Communication, and Media Art. Factorization machine (FM) can ...
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Article
Efficiently Writing Bragg Grating in High-Birefringence Elliptical Microfiber for Label-Free Immunosensing with Temperature Compensation
Immunosensor is a powerful tool in healthcare and clinic, food and drug industry, and environmental protection. Label-free fiber-optic immunosensors have shown a myriad of advantages, such as high sensitivity,...
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Article
Video Question Answering: a Survey of Models and Datasets
Video question answering (VideoQA) automatically answers natural language question according to the content of videos. It promotes the development of online education, scenario analysis, video content retrievi...
