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Article
Echocardiographic Measurements in Normal Chinese Adults (EMINCA) II focusing on left ventricular and left atrial size and function by three-dimensional echocardiography
Current guidelines encourage large studies in a diverse population to establish normal reference ranges for three-dimensional (3D) echocardiography for different ethnic groups. This study was designed to estab...
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Article
The association between noise and pregnancy complications: a systematic review and meta-analysis
Noise exposure during pregnancy may be correlated with a higher risk of pregnancy complications, such as hypertensive disorders of pregnancy (HDP), gestational diabetes mellitus (GDM), and pre-eclampsia (PE). ...
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Article
Open AccessDose-response associations of triglyceride to high-density lipoprotein cholesterol ratio and triglyceride–glucose index with arterial stiffness risk
The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and triglyceride-glucose (TyG) index are novel indexes for insulin resistance (IR). We aimed to evaluate associations of TG/HDL-C and T...
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Article
Open AccessTargeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE−/− Mice
Clearance of apoptotic cells by efferocytosis is crucial for prevention of atherosclerosis progress, and impaired efferocytosis contributes to the aggravated atherosclerosis.
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Article
Correlation of heavy metals’ exposure with the prevalence of coronary heart disease among US adults: findings of the US NHANES from 2003 to 2018
We sought to explore the association between heavy metal exposure and coronary heart disease (CHD) based on data from the US National Health and Nutrition Examination Survey (NHANES, 2003–2018). In the analyse...
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Article
Long-Term Exposure to Traffic Noise and Risk of Incident Cardiovascular Diseases: a Systematic Review and Dose-Response Meta-Analysis
While noise pollution from transportation has become an important public health problem, the relationships between different sources of traffic noise and cardiovascular diseases (CVDs) remain inconclusive. A c...
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Chapter and Conference Paper
Application of Association Rule Mining Algorithm in Civil Engineering Optimization Design
Engineering optimization design is a dynamic process of repeatedly analyzing and evaluating structure, searching for optimization, modifying design and analyzing and evaluating structure. Each intermediate res...
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Chapter and Conference Paper
Application of BIM + GIS Technology in Smart City 3D Design System
Smart city is a new concept and model of urban development in recent years. It is another major breakthrough in scientific and technological progress. Buildings are an important part of urban construction. Thi...
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Article
Open AccessAn optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency
Exosome mediated mRNA delivery is a promising strategy for the treatment of multiple diseases. However, the low yield of exosomes is a bottleneck for clinical translation. In this study, we boosted exosome pro...
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Article
Open AccessUltrasound triggered topical delivery of Bmp7 mRNA for white fat browning induction via engineered smart exosomes
Efficient and topical delivery of drugs is essential for maximized efficacy and minimized toxicity. In this study, we aimed to design an exosome-based drug delivery platform endowed with the ability of escapin...
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Chapter
3D Printing of Cardiomyopathy
Cardiomyopathy is a disease which involves heart tissue and is characterized by abnormal heart structure, heart failure, and arrhythmia, with great heterogeneity and diversity [1]. Cardiomyopathy can be classi...
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Article
Lung ultrasonography versus chest CT in COVID-19 pneumonia: a two-centered retrospective comparison study from China
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Article
Open AccessAssessment of left ventricular energy loss using vector flow map** in patients with stages 1–3 chronic kidney disease
Patients with chronic kidney disease (CKD) experience abnormality of intracardiac blood flow status during early-stages of disease. Left ventricular energy loss (EL) derived from vector flow map** (VFM) repr...
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Article
Open AccessLung ultrasound findings in patients with COVID-19 pneumonia
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Article
Self-transforming ultrathin α-Co(OH)2 nanosheet arrays from metal-organic framework modified graphene oxide with sandwichlike structure for efficient electrocatalytic oxygen evolution
Develo** efficient and low-cost electrocatalysts for oxygen evolution reaction (OER) with high electrochemical activity and durability for diverse renewable and sustainable energy technologies remains challe...
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Article
Stiffening of aorta is more preferentially associated with rheumatoid arthritis than peripheral arteries
The objective of this study is to investigate the relative impact of rheumatoid arthritis (RA) and other factors on arterial stiffness of different regions assessed by regional pulse wave velocity (PWV). Seven...
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Article
Lactobacillus supplementation prevents cisplatin-induced cardiotoxicity possibly by inflammation inhibition
Cardiotoxicity of chemotherapy exerts as the main hurdle for prognosis, while whether cisplatin causes severe cardiotoxicity remains largely unknown. Accumulating evidence reveals that intestinal microbiota fu...
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Article
Open AccessA Simple Method for Noninvasive Quantification of Pressure Gradient Across the Pulmonary Valve
Pressure gradient across the pulmonary valve (PVPG) is an important hemodynamic variable used in the management of patients with cardiovascular and pulmonary disease. However, a reliable noninvasive method is ...
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Article
Open AccessEWAS: epigenome-wide association studies software 1.0 – identifying the association between combinations of methylation levels and diseases
Similar to the SNP (single nucleotide polymorphism) data, there is non-random association of the DNA methylation level (we call it methylation disequilibrium, MD) between neighboring methylation loci. For the ...
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Article
Open AccessComparisons of the survival time of patients with ovarian cancer adopting post-operative chemotherapy by use of paclitaxel combined with carboplatin or nedaplatin
The current study aims to evaluate and compare the efficacy of post-operative chemotherapy using paclitaxel plus carboplatin or nedaplatin in patients with ovarian cancer, as well as the effects of different c...