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Article
Open AccessGut fungi of black-necked cranes (Grus nigricollis) respond to dietary changes during wintering
Migratory birds exhibit heterogeneity in foraging strategies during wintering to cope with environmental and migratory pressures, and gut bacteria respond to changes in host diet. However, less is known about ...
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Article
Open AccessGenetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders
Psychiatric disorders are highly heritable yet polygenic, potentially involving hundreds of risk genes. Genome-wide association studies have identified hundreds of genomic susceptibility loci with susceptibili...
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Article
Enhanced low-temperature activity of toluene combustion over Ce-modified Co3O4 catalyst by weakening Co−O strength
In this study, a series of Ce-modified Co3O4 catalysts were prepared by co-precipitation. The influence of Ce/(Ce + Co) ratio on the catalyst microstructure and catalytic oxidation performance of toluene were sys...
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Chapter and Conference Paper
Root Cause Analysis Based on Trace for Mobile Network Problem
During the network operation, certain definite factors lead to the occurrence of some abnormal events, which will directly affect the service perception of users. There is a lack of expert talent, insufficient...
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Chapter and Conference Paper
Weak Coverage Analysis Method for Mobile Networks Based on Machine Learning
Coverage is the foundation of mobile network. Therefore, one of the important tasks for mobile network operators is to improve the capability of network coverage so as to meet the requirement of user perceptio...
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Article
Microseismic Monitoring of Hydraulic Fracture Propagation and Seismic Risks in Shale Reservoir with a Steep Dip Angle
Hydraulic fracturing is an essential technique to increase reservoir permeability and enhance the production of shale gas. When the dip angle is steep and geological condition is complex, hydraulic fractures m...
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Article
Open AccessXDeathDB: a visualization platform for cell death molecular interactions
Lots of cell death initiator and effector molecules, signalling pathways and subcellular sites have been identified as key mediators in both cell death processes in cancer. The XDeathDB visualization platform ...
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Article
Numerical modeling of the dynamic variation in multiphase CH4 during CO2 enhanced gas recovery from depleted shale reservoirs
Regarding CO2 enhanced shale gas recovery, this work focuses on changes in the multiphase (free/adsorbed) CH4 in the process of CO2 enhanced shale gas recovery, by utilizing a rigorous numerical model with real g...
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Article
Open AccessMatched cohort study of germline BRCA mutation carriers with triple negative breast cancer in brightness
In the BrighTNess trial, carboplatin added to neoadjuvant chemotherapy (NAC) was associated with increased pathologic complete response (pCR) rates in patients with stage II/III triple-negative breast cancer (...
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Article
C1 Esterase Inhibition: Targeting Multiple Systems in COVID-19
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Article
PKCβ/NF-κB pathway in diabetic atrial remodeling
Atrial remodeling in diabetes is partially attributed to NF-κB/TGF-β signal transduction pathway activation. We examined whether the hyperglycemia-induced increased expression of NF-κB/TGF-β was dependent upon...
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Article
Sol–gel citrate procedure to synthesize Ag/Co3O4 catalysts with enhanced activity for propane catalytic combustion
The Co3O4 and Ag/Co3O4 catalysts with varying content of Ag were fabricated via sol–gel citrate procedure, which were used for propane total oxidation. First, Ag+ and/or Co2+ ions coordinate with citric acid to f...
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Article
p300/CBP inhibition enhances the efficacy of programmed death-ligand 1 blockade treatment in prostate cancer
Blockade of programmed death-ligand 1 (PD-L1) by therapeutic antibodies has shown to be a promising strategy in cancer therapy, yet clinical response in many types of cancer, including prostate cancer (PCa), i...
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Article
Open AccessSCNrank: spectral clustering for network-based ranking to reveal potential drug targets and its application in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy. Due to its wide heterogeneity, PDAC acts aggressively and responds poorly to most chemotherapies, causing an urgent need for th...
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Article
Open AccessIntegration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma
While most pediatric sarcomas respond to front-line therapy, some bone sarcomas do not show radiographic response like soft-tissue sarcomas (rhabdomyosarccomas) but do show 90% necrosis. Though, new therapies ...
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Article
Open AccessCharacteristics, capability, and origin of shale gas desorption of the Longmaxi Formation in the southeastern Sichuan Basin, China
Shale gas desorption and loss is a serious and common phenomenon in the Sichuan Basin. The characteristics, capability, and origin of shale gas desorption are significant for understanding the shale gas reserv...
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Article
Solar-responsive sole TiO2 nanotube arrays with high photocatalytic activity prepared by one-step anodic oxidation
We prepared sole TiO2 nanotube arrays (NAs) using one-step and two-step anodic oxidation followed by annealing. These TiO2 NAs were characterized by X-ray diffraction (XRD), Raman spectrum, scanning electron micr...
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Article
Temperature sensing behavior in Yb3+–Tb3+ and Eu3+ doped Ca2Gd8(SiO4)6O2 phosphors based on upconversion and downshifting luminescence
To develop new phosphor materials for optical temperature sensing application, a series of Yb3+–Tb3+ and Eu3+ doped Ca2Gd8(SiO4)6O2 (CGS) phosphors were designed by solid-state reaction method. Upon 980 nm excita...
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Article
Constructing novel Bi2SiO5–Bi2O3 hybrid loaded sepiolite with enhanced visible light photocatalytic activity
Bi2O3 and Bi2SiO5–Bi2O3 hybrid loaded sepiolite photocatalysts were synthesized via chemical precipitation method by tuning ratio of Bi3+ and sepiolite. The samples were characterized and photodegradation of mala...
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Article
PMTDS: a computational method based on genetic interaction networks for Precision Medicine Target-Drug Selection in cancer
Precision medicine attempts to tailor the right therapy for the right patient. Recent progress in large-scale collection of patents’ tumor molecular profiles in The Cancer Genome Atlas (TCGA) provides a founda...
