21 Result(s)

Article

Author Correction: Fructose-1,6-bisphosphatase 1 dephosphorylates and inhibits TERT for tumor suppression

Min Li, Zheng Wang, **g**g Tao, Hongfei Jiang, Huang Yang… in Nature Chemical Biology (2024)

Article

Menstrual blood-derived mesenchymal stem cells combined with collagen I gel as a regenerative therapeutic strategy for degenerated disc after discectomy in rats

Annulus fibrosis (AF) defects have been identified as the primary cause of disc herniation relapse and subsequent disc degeneration following discectomy. Stem cell-based tissue engineering offers a promising a...

Li Yu, Honghao Wu, Shumei Zeng, **aojian Hu, Yuxu Wu… in Stem Cell Research & Therapy (2024)

Article

CircMAST1 inhibits cervical cancer progression by hindering the N4-acetylcytidine modification of YAP mRNA

Cervical cancer (CCa) is the fourth most common cancer among females, with high incidence and mortality rates. Circular RNAs (circRNAs) are key regulators of various biological processes in cancer. However, th...

Chunyu Zhang, Li Yuan, Qiaojian Zou, Caixia Shao… in Cellular & Molecular Biology Letters (2024)

Article

Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis

Metastases within liver or the brain are the most common causes of mortality from lung cancer (LC). Predicting liver or brain metastases before having evidence from imaging of the tumors is challenging but imp...

Sini Li, Yan Qu, Lihui Liu, Xue Zhang, Yan He, Chao Wang, Yufeng Guo… in Cell & Bioscience (2023)

Article

EZH2-mediated epigenetic silencing of tumor-suppressive let-7c/miR-99a cluster by hepatitis B virus X antigen enhances hepatocellular carcinoma progression and metastasis

Hepatitis B virus (HBV)-encoded X antigen, HBx, assists in the development of hepatocellular carcinoma (HCC) through complex mechanisms. Our results provide new insights into the EZH2 epigenetic repression of ...

Chen-Shiou Wu, Yi-Chung Chien, Chia‐Jui Yen, Jia-Yan Wu… in Cancer Cell International (2023)

Article

Inhibition of ERK downregulates autophagy via mitigating mitochondrial fragmentation to protect SH-SY5Y cells from OGD/R injury

Cerebral ischemia-reperfusion injury (CIRI) is the main cause leading to high mortality and neurological disability in patients with cardiac arrest/cardiopulmonary resuscitation (CA/CPR). Our previous study fo...

Zhang-Li Yuan, Yan-Zi Mo, De-Li Li, Lu **e… in Cell Communication and Signaling (2023)

Article

Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism

Gastric cancer (GC) is among the most lethal malignancies due to its poor early diagnosis and high metastasis rate, and new therapeutic targets are urgently needed to develop effective anti-GC drugs. Glutathio...

Handong Xu, Can Hu, Yi Wang, Yunfu Shi, Li Yuan, **gli Xu, Yanqiang Zhang… in Oncogene (2023)

Article

Retraction Note: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/ NQO1 axis via downregulating miR-450b-5p

Wei Huang, Guangqing Shi, Zhong Yong, Jian Li, Juan Qiu, Yan Cao… in Cell Death & Disease (2023)

Article

Human menstrual blood-derived stem cells reverse sorafenib resistance in hepatocellular carcinoma cells through the hyperactivation of mitophagy

Sorafenib is a first-line drug targeting the RTK-MAPK signalling pathway used to treat advanced hepatocellular carcinoma (HCC). However, tumour cells readily develop sorafenib resistance, limiting long-term th...

Sining Zhou, Yiming Liu, Qi Zhang, Huikang Xu, Yangxin Fang… in Stem Cell Research & Therapy (2023)

Article

CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability

Lymph node (LN) metastasis is one of the most malignant clinical features in patients with cervical cancer (CCa). Understanding the mechanism of lymph node metastasis will provide treatment strategies for pati...

Chunyu Zhang, Hongye Jiang, Li Yuan, Yuandong Liao, Pan Liu, Qiqiao Du… in Oncogene (2023)

Article

Legacy of Hongxi Su: Pioneer of Chinese Cardiosurgery

Sumin Yang, Haoyu Hu, **n Zheng, Shizhong Wang, Li Yuan in Protein & Cell (2022)

Article

EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

Epstein–Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily associated with multiple lymphoid and epithelial cancers, including nasopharyngeal carcinoma (NPC). However, its ass...

Li Yuan, Shibing Li, Qiuyan Chen, Tianliang **a… in Cell Death & Differentiation (2022)

Article

Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis

Circular RNAs (circRNAs) are known to act as key regulators in a variety of malignancies. However, the role of circRNAs in cervical cancer (CCa) remains largely unknown. Herein, we demonstrated that a circRNA ...

Chunyu Zhang, Pan Liu, Jiaming Huang, Yuandong Liao, Chaoyun Pan… in Cell Death & Disease (2021)

Article

SIRT1 attenuates renal fibrosis by repressing HIF-2α

Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD⁺)-dependent deacetylase belonging to class III histone deacetylases. Previous studies have shown that SIRT1 is involved in kidney physiology regulatio...

Peipei Li, Yue Liu, **aogang Qin, Kairen Chen, Ruiting Wang… in Cell Death Discovery (2021)

Article

Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects

Idiopathic pulmonary fibrosis is a kind of diffuse interstitial lung disease, the pathogenesis of which is unclear, and there is currently a lack of good treatment to improve the survival rate. Human menstrual...

**n Chen, Yi Wu, Yanling Wang, Lijun Chen, Wendi Zheng… in Stem Cell Research & Therapy (2020)

Article

RETRACTED ARTICLE: Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p

Dysregulation of RKIP and NRF2 has been widely involved in the therapy resistance of multiple malignances, however, their relation and the corresponding mechanisms, especially in radiation response, have not b...

Wei Huang, Guangqing Shi, Zhong Yong, Jian Li, Juan Qiu, Yan Cao… in Cell Death & Disease (2020)

Article

MiR-369-3p participates in endometrioid adenocarcinoma via the regulation of autophagy

The aim of this study is to examine miRNA profiling and miR-369-3p participates in endometrioid adenocarcinoma (EEC) via the regulation of autophagy.

** Liu, Chengbin Ma, Qiongwei Wu, Wenying Zhang, Cao Wang… in Cancer Cell International (2019)

Article

CRLF1 promotes malignant phenotypes of papillary thyroid carcinoma by activating the MAPK/ERK and PI3K/AKT pathways

Papillary thyroid carcinoma (PTC) is the one of the most common types of endocrine cancer and has a heterogeneous prognosis. Tumors from patients with poor prognosis may differentially express specific genes. ...

Shi-Tong Yu, Qian Zhong, Ren-Hui Chen, ** Han, Shi-Bing Li… in Cell Death & Disease (2018)

Article

Mettl3-mediated m⁶A regulates spermatogonial differentiation and meiosis initiation

METTL3 catalyzes the formation of N⁶-methyl-adenosine (m⁶A) which has important roles in regulating various biological processes. However, the in vivo function of Mettl3 remains largely unknown in mammals. Here w...

Kai Xu, Ying Yang, Gui-Hai Feng, Bao-Fa Sun, Jun-Qing Chen, Yu-Fei Li… in Cell Research (2017)

Article

Spore formation in plants: SPOROCYTELESS and more

Plant reproduction is initiated by the specification of sporocytes that form haploid spores through meiosis. A new study in Arabidopsis published in Cell Research shows how the product of SPOROCYTELESS/NOZZLE, a ...

Li Yuan, Venkatesan Sundaresan in Cell Research (2015)